儿童新型抗癫痫药物
New antiepileptic drugs in childhood.
作者信息
Verrotti A, Trotta D, Morgese G, Chiarelli F
机构信息
Department of Paediatrics, University of Chieti, Chieti, Italy.
出版信息
Panminerva Med. 2002 Sep;44(3):221-5.
In recent years, many new antiepileptic drugs have been available for the treatment of epilepsy in pediatric age. In this review, we describe these new antiepileptic drugs (vigabatrin, lamotrigine, felbamate, gabapentin, tiagabine, topiramate) which can be used together with "old" antiepileptic drugs (e.g. phenobarbital, valproate, etc.). We report their mechanisms of action, effectiveness, dosage and side effects; moreover, some practical advice for their use in pediatric patients is given.
近年来，许多新型抗癫痫药物可用于治疗小儿癫痫。在本综述中，我们描述了这些新型抗癫痫药物（氨己烯酸、拉莫三嗪、非氨酯、加巴喷丁、噻加宾、托吡酯），它们可与“老一代”抗癫痫药物（如苯巴比妥、丙戊酸盐等）联合使用。我们报告了它们的作用机制、疗效、剂量和副作用；此外，还给出了一些在儿科患者中使用这些药物的实用建议。
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