Khavinson V Kh, Malinin V V, Chalisova N I, Grigor'ev E I
St. Petersburg Institute of Bioregulation and Gerontology, North-Western Branch, Russian Academy of Medical Sciences, 3, Dynamo Prospect, 197110 St. Petersburg, Russia.
Adv Gerontol. 2002;9:95-100.
There was studied the effect of polypeptide preparations isolated from the cerebral cortex (Cortexin), epiphysis (Epithalamin), liver (Hepalin), thymus (Thymalin) and small synthetic peptides--Cortagen, Epitalon, Livagen, Vilon on the development of explants from the cerebral cortex, brain subcortical structures, liver and thymus of rats of various age. With respect to the applied concentrations of the investigated peptides, they exerted tissue-specific effects in the organ-typical culture of animal tissues.
研究了从大脑皮层分离的多肽制剂（脑复素）、松果体（表丙氨酸）、肝脏（肝素）、胸腺（胸腺素）以及小的合成肽——可体松、表睾酮、肝维隆、维隆对不同年龄大鼠大脑皮层、脑皮质下结构、肝脏和胸腺外植体发育的影响。就所研究肽的应用浓度而言，它们在动物组织的器官典型培养中发挥了组织特异性作用。
