Chalisova N I, Khavinson V Kh, Davydenko V V, Dorovskiĭ A A, Verbovaia T A, Penniiaĭnen V A
Pavlov Institute of Physiology RAS, Institute of Bioregulation and Gerontology RAMS, St. Petersburg.
Tsitologiia. 2000;42(12):1144-7.
Some natural peptides, referred to as cytomedines, were isolated from different organs: cortexin and epithalamin (both from the brain), cordialin (heart), hepalin (liver) and thymalin (thymus),--to test their stimulating effects on the growth in organotypic culture of different tissue explants taken from 3 day old rats. It has been found that these peptides exerted their obvious stimulating effects on the growth of the cultured explants, compared to the control, if taken in the respective concentrations: 100, 50, 50, 100 and 5 ng/ml. Thus, these cytomedins can be used in the clinical practice for stimulating reparative processes in the appropriate tissues.
一些被称为细胞调节素的天然肽，是从不同器官中分离出来的：皮质素和上皮生长素（均来自大脑）、强心素（心脏）、肝生长素（肝脏）和胸腺生长素（胸腺），——用于测试它们对取自3日龄大鼠的不同组织外植体在器官型培养中的生长刺激作用。已经发现，与对照组相比，如果以各自的浓度：100、50、50、100和5 ng/ml使用，这些肽对培养的外植体生长具有明显的刺激作用。因此，这些细胞调节素可用于临床实践，以刺激相应组织中的修复过程。
