Caccamese J F, Ord R A
Division of Oral and Maxillofacial Surgery, University of Maryland Medical Systems, Baltimore 21201, USA.
Int J Oral Maxillofac Surg. 2002 Apr;31(2):136-9. doi: 10.1054/ijom.2001.0221.
The purpose of this paper is to review our experience with mucoepidermoid carcinoma (MEC), a rare tumour in minor salivary glands, in a small series of paediatric patients. A retrospective analysis of minor salivary gland tumours seen by one surgeon from March 1991 to December 1999 was undertaken. A total of 58 cases were identified and of these, five (9%) occurred in children. There were 23 cases of MEC, four (17%) of which occurred in patients under the age of 18 who presented with T1 or T2N0M0 low- to intermediate-grade MEC of the palate and adjacent structures. These patients form the basis of this study. All patients were treated with wide local excision, obtaining tumour-free margins, and followed for a mean number of 58 months. None of these tumours invaded bone and resection of bone was not performed in any case as the periosteum was intact and the tumours were low to intermediate grade. To date, all patients remain free of disease. One patient who went elsewhere for treatment, was treated with local resection only, and has also experienced no recurrence. Wide local excision is the treatment of choice for low to intermediate grade MEC of the minor salivary glands in paediatric patients.
本文旨在回顾我们在一小部分儿科患者中治疗黏液表皮样癌(MEC)的经验,黏液表皮样癌是一种罕见的小唾液腺肿瘤。对一位外科医生在1991年3月至1999年12月期间诊治的小唾液腺肿瘤进行了回顾性分析。共识别出58例病例,其中5例(9%)发生在儿童患者中。有23例黏液表皮样癌,其中4例(17%)发生在18岁以下患者中,这些患者表现为腭部及相邻结构的T1或T2N0M0低至中度分级的黏液表皮样癌。这些患者构成了本研究的基础。所有患者均接受了广泛局部切除,切缘无肿瘤残留,并平均随访了58个月。这些肿瘤均未侵犯骨质,由于骨膜完整且肿瘤为低至中度分级,因此在任何情况下均未进行骨切除。迄今为止,所有患者均无疾病复发。有1例患者去其他地方接受治疗,仅接受了局部切除,也未出现复发。广泛局部切除是小儿患者小唾液腺低至中度分级黏液表皮样癌的首选治疗方法。