Ross L, Boesen E H, Dalton S O, Johansen C
Department of Psychosocial Cancer Research, Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.
Eur J Cancer. 2002 Jul;38(11):1447-57. doi: 10.1016/s0959-8049(02)00126-0.
The aim of this review was to evaluate the scientific evidence for an effect of psychosocial intervention on survival from cancer and well-being and in particular on anxiety and depression. A literature search yielded 43 randomised studies of psychosocial intervention. Four of the eight studies in which survival was assessed showed a significant effect, and the effect on anxiety and depression was also inconsistent, indicating three possible explanations: (i) only some of the intervention strategies affect prognosis and/or well-being and in only certain patient groups; (ii) the effect was weak, so that inconsistent results were found in the generally small study populations; or (iii) the effect was diluted by the inclusion of unselected patient groups rather than being restricted to patients in need of psychosocial support. Thus, large-scale studies with sound methods are needed in which eligible patients are screened for distress. Meanwhile, the question of whether psychosocial intervention among cancer patients has a beneficial effect remains unresolved.
本综述的目的是评估心理社会干预对癌症患者生存及幸福感，尤其是对焦虑和抑郁影响的科学证据。文献检索得到了43项心理社会干预的随机研究。在八项评估生存情况的研究中，有四项显示出显著效果，对焦虑和抑郁的影响也不一致，这表明有三种可能的解释：（i）只有部分干预策略会影响预后和/或幸福感，且仅在特定患者群体中起作用；（ii）效果微弱，因此在通常规模较小的研究人群中发现了不一致的结果；或（iii）由于纳入了未经过筛选的患者群体，而非仅限于需要心理社会支持的患者，导致效果被稀释。因此，需要开展方法完善的大规模研究，对符合条件的患者进行痛苦筛查。与此同时，癌症患者的心理社会干预是否具有有益效果这一问题仍未得到解决。
