Mukherjee Anindita, Mazumder Koustav, Kaushal Vikrant, Ghoshal Sushmita
Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Palliat Care. 2017 Oct-Dec;23(4):399-402. doi: 10.4103/IJPC.IJPC_73_17.
Cancer patients receiving chemotherapy for their recurrent disease often report the presence of anxiety and depression.
In the study, we intended to find out the mental health status and overall quality of life (QOL) of such patients and to identify the effect of supportive psychotherapy.
Forty cancer patients undergoing second or subsequent line chemotherapy(CCT) were selected for psychotherapy session. Pre- and post-psychotherapy evaluation of anxiety and depression was determined by hospital anxiety depression scale. The QOL was measured before and after psychotherapy sessions by using WHO QOL-BREF scale.
Statistical analysis was done by paired -test, using SPSS V.20.
Among 40 patients, 17 patients had breast cancer, and the remaining had ovarian cancer. All breast cancer and 19 ovarian cancer patients were receiving 2 line CCT. Four ovarian cancer patients were undergoing 3 line CCT. Results indicated that mean scores (± standard deviation) of anxiety 13.95 (±4) and depression 15.5 (±4.4) both exceeded the cut-off score of 11 and mean score of QOL physical health 29.77 (±10.1), psychological health 31.3 (±10.1), social relationship 35.1 (±9.6), and environmental condition 25.9 (±9.9) was below cut-off score of 60. After psychotherapy, there was significant reduction in anxiety ( < 0.01), depression ( < 0.01) and improvement on QOL physical heath ( = 0.02), psychological health ( < 0.01), environmental condition ( < 0.01), and social relationship ( < 0.01).
Supportive psychotherapy helps to reduce the level of anxiety, depression, and increase the QOL. Therefore, psychotherapeutic intervention should be encouraged along with chemotherapy to promote positive mental health and to obtain full benefit of their physical treatment.
接受化疗以治疗复发性疾病的癌症患者经常报告存在焦虑和抑郁情绪。
在本研究中，我们旨在了解此类患者的心理健康状况和总体生活质量（QOL），并确定支持性心理治疗的效果。
选择40例正在接受二线或后续化疗（CCT）的癌症患者进行心理治疗。通过医院焦虑抑郁量表对心理治疗前后的焦虑和抑郁情况进行评估。在心理治疗前后使用世界卫生组织生活质量简表（WHO QOL - BREF）对生活质量进行测量。
采用配对t检验进行统计分析，使用SPSS V.20软件。
40例患者中，17例患有乳腺癌，其余患有卵巢癌。所有乳腺癌患者和19例卵巢癌患者正在接受二线CCT治疗。4例卵巢癌患者正在接受三线CCT治疗。结果表明，焦虑的平均得分（±标准差）为13.95（±4），抑郁的平均得分15.5（±4.4）均超过临界值11，生活质量的身体健康平均得分29.77（±10.1）、心理健康平均得分31.3（±10.1）、社会关系平均得分35.1（±9.6）以及环境状况平均得分25.9（±9.9）均低于临界值60。心理治疗后，焦虑（P < 0.01）、抑郁（P < 0.01）显著降低，生活质量的身体健康（P = 0.02）、心理健康（P < 0.01）、环境状况（P < 0.01）和社会关系（P < 0.01）均有改善。
支持性心理治疗有助于降低焦虑和抑郁水平，并提高生活质量。因此，应鼓励在化疗的同时进行心理治疗干预，以促进积极的心理健康，并使患者从身体治疗中获得最大益处。
