Petjom Supinda, Chaiwun Benjaporn, Settakorn Jongkolnee, Visrutaratna Pannee, Rangdaeng Samreung, Thorner Paul S
Department of Pathology, Faculty of Medicine, Chiang Mai University, Thailand.
Ann Neurol. 2002 Jul;52(1):99-101. doi: 10.1002/ana.10215.
Angiostrongylus cantonensis is the most common cause of eosinophilic meningitis and meningoencephalitis. Almost all cases are self-limiting and are diagnosed by cerebrospinal fluid eosinophilia and enzyme-linked immunosorbent assay; pathology reports are restricted to postmortem samples from lethal cases. We report on what we believe is the first case of A. cantonensis infection diagnosed by biopsy in a living patient. The spinal cord was biopsied because of the unusual clinical presentation of a myelopathy without meningeal symptoms, together with a mass lesion that was clinically and radiologically diagnosed as a spinal cord tumor.
广州管圆线虫是嗜酸性粒细胞性脑膜炎和脑膜脑炎最常见的病因。几乎所有病例都是自限性的,通过脑脊液嗜酸性粒细胞增多和酶联免疫吸附测定进行诊断;病理报告仅限于致命病例的尸检样本。我们报告了我们认为是首例在活体患者中通过活检诊断出广州管圆线虫感染的病例。由于出现无脑膜症状的脊髓病的不寻常临床表现,以及临床上和放射学上诊断为脊髓肿瘤的肿块病变,对脊髓进行了活检。