Morassutti Alessandra Loureiro, Thiengo Silvana Carvalho, Fernandez Monica, Sawanyawisuth Kittisak, Graeff-Teixeira Carlos
Laboratório de Biologia Parasitária, Faculdade de Biociências, Pontifícia Universidade do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Laboratório de Malacologia, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brasil.
Mem Inst Oswaldo Cruz. 2014 Jul;109(4):399-407. doi: 10.1590/0074-0276140023.
Eosinophilic meningitis (EoM) is an acute disease that affects the central nervous system. It is primarily caused by infection with the nematode Angiostrongylus cantonensis. This infection was previously restricted to certain Asian countries and the Pacific Islands, but it was first reported in Brazil in 2007. Since then, intermediate and definitive hosts infected with A. cantonensis have been identified within the urban areas of many states in Brazil, including those in the northern, northeastern, southeastern and southern regions. The goals of this review are to draw the attention of the medical community and health centres to the emergence of EoM in Brazil, to compile information about several aspects of the human infection and mode of transmission and to provide a short protocol of procedures for the diagnosis of this disease.
嗜酸性粒细胞性脑膜炎(EoM)是一种影响中枢神经系统的急性疾病。它主要由感染广州管圆线虫引起。这种感染以前局限于某些亚洲国家和太平洋岛屿,但2007年在巴西首次报道。从那时起,在巴西许多州的城市地区,包括北部、东北部、东南部和南部地区,均已发现感染广州管圆线虫的中间宿主和终宿主。本综述的目的是引起医学界和卫生中心对巴西嗜酸性粒细胞性脑膜炎出现情况的关注,汇编有关人类感染及传播方式几个方面的信息,并提供该疾病诊断的简短程序方案。