Reinisch Lou
Department of Otolaryngology, Vanderbilt Bill Wilkerson Center for Otolaryngology and Communication Sciences, Nashville, Tennessee 37232-2550, USA.
Lasers Surg Med. 2002;30(5):381-8. doi: 10.1002/lsm.10046.
To effectively deliver laser light into the skin for non-ablative resurfacing, hair removal, and other applications, one must account for scatter, absorption, and thermal diffusion. A novel method to control the penetration of laser light into tissue is proposed. This method uses the incident beam diameter, the pulse duration, and the intrinsic light scattering of tissues such as skin to limit the laser light penetration and thermal damage. We term this innovative laser delivery concept 'scatter-limited phototherapy'.
STUDY DESIGN/MATERIALS AND METHODS: This study demonstrates how the delivery mechanism simplifies the non-ablative treatment of sun-damaged skin. Calculations are based upon Gaussian scatter of light and isotropic thermal diffusion. Calculations of light distribution and profiles of temperature increase are created.
Using an optical fiber delivery system with the appropriate diameter, coupled with skin surface protection, one can create thermal damage at a given depth with preservation of the epidermis.
Scatter-limited phototherapy is a predictive model, allowing one to design better laser delivery systems. Scatter-limited phototherapy should also be applicable to other fields of dermatologic surgery, such as hair removal and the treatment of vascular lesions. Additionally, other medical specialties will be able to use the concept of scatter-limited phototherapy to predict and better understand laser-tissue interactions.
为了有效地将激光导入皮肤以进行非剥脱性皮肤重建、脱毛及其他应用,必须考虑散射、吸收和热扩散。本文提出一种控制激光穿透组织的新方法。该方法利用入射光束直径、脉冲持续时间以及皮肤等组织的固有光散射来限制激光穿透和热损伤。我们将这种创新的激光传输概念称为“散射受限光疗法”。
研究设计/材料与方法:本研究展示了该传输机制如何简化对受阳光损伤皮肤的非剥脱性治疗。计算基于光的高斯散射和各向同性热扩散。创建了光分布和温度升高曲线的计算。
使用具有合适直径的光纤传输系统,并结合皮肤表面保护,能够在给定深度造成热损伤同时保留表皮。
散射受限光疗法是一种预测模型,可用于设计更好的激光传输系统。散射受限光疗法也应适用于皮肤科手术的其他领域,如脱毛和血管病变的治疗。此外,其他医学专业将能够利用散射受限光疗法的概念来预测并更好地理解激光与组织的相互作用。