Couillault Carole, Ewbank Jonathan J
Centre d'Immunologie de Marseille-Luminy, INSERM/CNRS/Université de la Mediterranée, Case 906, 13288 Marseille Cedex 9, France.
Infect Immun. 2002 Aug;70(8):4705-7. doi: 10.1128/IAI.70.8.4705-4707.2002.
Practically and ethically attractive as model systems, invertebrate organisms are increasingly recognized as relevant for the study of bacterial pathogenesis. We show here that the nematode Caenorhabditis elegans is susceptible to a surprisingly broad range of bacteria and may constitute a useful model for the study of both pathogens and symbionts.
作为模型系统,无脊椎动物在实际应用和伦理方面都颇具吸引力,它们越来越被认为与细菌致病机制的研究相关。我们在此表明,线虫秀丽隐杆线虫对种类惊人的多种细菌敏感,可能构成研究病原体和共生体的有用模型。