Hannuksela M, Ahvonen P
Ann Clin Res. 1975 Dec;7(6):368-73.
In 1969-1973, acute yersiniosis was diagnosed in 30 cases of erythema nodosum (EN), in 6 cases of EN and simultaneous erythema multiforme (EM), in one case of EN and erythema figuratum, in one case of EM, and in one case of drug eruption-like exanthema, respectively. During these years, 180 patients with EN due to other causes were seen. The most marked difference in the clinical course between yersiniosis and other cases was the duration of the eruption. EN nodules in yersinia EN faded away in 4 weeks in all but one case while the 4-week cure rate among the other patients with EN was only 37%. There were two types of EM lesions, namely cockade-like lesions and vesicopapules. They usually appeared some days before or together with EN nodules and they disappeared within 2 weeks without any scarring. Yersiniosis was caused by Y. enterocolitica serotype 3 in 19 cases. Y.ent. serotype 9 in 17 cases, and Y.pseudotuberculosis in 3 cases. Of the patients, 21 suffered from abdominal pains and/or diarrhoea prior to skin manifestations, but 11 had no pregastrointestinal symptoms resembling those of yersiniosis.
1969年至1973年期间,分别在30例结节性红斑(EN)、6例EN合并多形红斑(EM)、1例EN合并地图状红斑、1例EM以及1例药疹样皮疹患者中诊断出急性耶尔森菌病。在这些年里,还诊治了180例由其他原因引起的EN患者。耶尔森菌病与其他病例在临床病程上最显著的差异在于皮疹持续时间。除1例患者外,耶尔森菌病相关的EN结节在4周内全部消退,而其他EN患者的4周治愈率仅为37%。EM病变有两种类型,即帽徽样病变和水疱丘疹。它们通常在EN结节出现前几天或同时出现,并在2周内消失,不留任何瘢痕。19例耶尔森菌病由小肠结肠炎耶尔森菌3型引起,17例由小肠结肠炎耶尔森菌9型引起,3例由假结核耶尔森菌引起。这些患者中,21例在皮肤表现出现之前有腹痛和/或腹泻症状,但11例没有类似耶尔森菌病的胃肠道症状。