Ricketts C, Jacobs A, Cavill I
Br J Haematol. 1975 Sep;31(1):65-75. doi: 10.1111/j.1365-2141.1975.tb00833.x.
Existing ferrokinetic methods do not provide a direct and quantitative measurement of effective and ineffective red cell production. A new method is described for calculating the daily uptake of iron by maturing red cells and the mean red cell lifespan. Ineffective erythropoiesis and non-erythroid iron turnover are also measured. The method involves standard laboratory techniques but the analysis requires access to a computer. The preliminary results suggest that it will be a clinically useful tool for the investigation of erythroid disorders.
现有的铁动力学方法无法直接定量测量有效和无效红细胞生成。本文描述了一种新方法，用于计算成熟红细胞每日的铁摄入量以及平均红细胞寿命。同时也可测量无效红细胞生成和非红细胞铁周转情况。该方法采用标准实验室技术，但分析过程需要使用计算机。初步结果表明，它将成为研究红细胞疾病的一种临床有用工具。
