Westerman M P
Br J Haematol. 1975 Sep;31(1):87-94. doi: 10.1111/j.1365-2141.1975.tb00835.x.
The present study has examined the relationship and significance of hypocholesterolaemia to anaemia and to the red cell. The level of plasma cholesterol is closely related to haematocrit levels both initially and throughout the course of the anaemias associated with hypocholesterolaemia. The association is maintained, regardless of the cause of the haematocrit change, i.e. transfusion or response to treatment. Hypocholesterolaemia does not affect the red cell, i.e. its survival, cholesterol concentration or osmotic fragility and occurs in a diverse group of anaemias. As such, it is not causally related to anaemia. The changes in plasma cholesterol are most likely related to its 'redistribution' or to plasma 'dilution', with contributory factors occurring. The presence of anaemia, even to a modest degree, would be important to consider when comparing cholesterol levels between groups of individuals.
本研究探讨了低胆固醇血症与贫血及红细胞之间的关系和意义。血浆胆固醇水平在最初以及整个与低胆固醇血症相关的贫血病程中均与血细胞比容水平密切相关。无论血细胞比容变化的原因是输血还是对治疗的反应，这种关联都持续存在。低胆固醇血症不影响红细胞，即其存活、胆固醇浓度或渗透脆性，且发生于多种贫血类型中。因此，它与贫血无因果关系。血浆胆固醇的变化很可能与其“重新分布”或血浆“稀释”有关，同时存在一些促成因素。在比较不同个体组之间的胆固醇水平时，即使是轻度贫血的存在也值得考虑。
