Neshev G, Stoianov S, Antonov P, Tomov T
Farmakol Toksikol. 1975 Jul-Aug;38(4):484-8.
It has been established that rosanol, obtained from bulgarian rose oil, averts fatal disturbances of the cardiac rhythm induced by calcium dichloride and also prevents the onset of severe changes on the electrocardiogram provoked by a high-frequency electric stimulation of the mesencephalic reticular formation and by an intravenous administration of high doses of norepinepharine. In experiments on mitochondria the authors make an attempt to explain this antiarhythmic effect of rosanol by stabilization of the membranous potential.
业已确定,从保加利亚玫瑰油中提取的玫瑰醇能避免二氯化钙引起的致命性心律失常,还能防止因中脑网状结构高频电刺激及静脉注射高剂量去甲肾上腺素所诱发的心电图严重变化。在对线粒体进行的实验中,作者试图通过稳定膜电位来解释玫瑰醇的这种抗心律失常作用。