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印度快速推广直接观察短程化疗策略

Rapid DOTS expansion in India.

作者信息

Khatri G R, Frieden Thomas R

机构信息

Directorate General of Health Services, Ministry of Health and Family Welfare, New Delhi, 110 011, India.

出版信息

Bull World Health Organ. 2002;80(6):457-63.

Abstract

Since late 1998 the coverage of the DOTS strategy in India has been expanded rapidly. In both 2000 and 2001 the country probably accounted for more than half the global increase in the number of patients treated under DOTS and by early 2002 more than a million patients were being treated in this way in India. As a result, nearly 200 000 lives were saved. The lessons learnt relate to the importance of the following elements of the programme: (1) getting the science right and ensuring technical excellence; (2) building commitment and ensuring the provision of funds and flexibility in their utilization; (3) maintaining focus and priorities; (4) systematically appraising each area before starting service delivery; (5) ensuring an uninterrupted drug supply; (6) strengthening the established infrastructure and providing support for staff; (7) supporting the infrastructure required in urban areas; (8) ensuring full-time independent technical support and supervision, particularly during the initial phases of implementation; (9) monitoring intensively and giving timely feedback; and (10) continuous supervision. Tuberculosis (TB) control still faces major challenges in India. To reach its potential, the control programme needs to: continue to expand so as to cover the remaining half of the country, much of which has a weaker health infrastructure than the areas already covered; increase its reach in the areas already covered so that a greater proportion of patients is treated; ensure sustainability; improve the patient-friendliness of services; confront TB associated with human immunodeficiency virus (HIV) infection. It is expected that HIV will increase the number of TB cases by at least 10% and by a considerably higher percentage if HIV becomes much more widespread. India's experience shows that DOTS can achieve high case-detection and cure rates even with imperfect technology and often with an inadequate public health infrastructure. However, this can only happen if the delivery programme is appropriately designed and effectively managed.

摘要

自1998年末以来,印度直接观察短程治疗(DOTS)策略的覆盖范围迅速扩大。在2000年和2001年,该国接受DOTS治疗的患者数量全球增量可能超过一半,到2002年初,印度有超过100万患者正接受此类治疗。结果,挽救了近20万人的生命。汲取的经验教训涉及该项目以下要素的重要性:(1)掌握正确科学并确保技术卓越;(2)确立承诺并确保资金提供及其使用的灵活性;(3)保持专注和优先事项;(4)在开始服务提供之前系统评估每个领域;(5)确保不间断的药品供应;(6)加强现有基础设施并为工作人员提供支持;(7)支持城市地区所需的基础设施;(8)确保全职独立技术支持和监督,特别是在实施初期阶段;(9)进行密集监测并及时反馈;以及(10)持续监督。结核病控制在印度仍面临重大挑战。为发挥其潜力,控制项目需要:继续扩大以覆盖该国另一半地区,其中许多地区的卫生基础设施比已覆盖地区薄弱;在已覆盖地区扩大覆盖范围,以便治疗更大比例的患者;确保可持续性;提高服务对患者的友好程度;应对与人类免疫缺陷病毒(HIV)感染相关的结核病。预计HIV将使结核病病例数至少增加10%,如果HIV传播更为广泛,增幅会更高。印度的经验表明,即使技术不完善且公共卫生基础设施往往不足,DOTS仍可实现高病例发现率和治愈率。然而,只有在交付项目设计得当且管理有效时才会如此。

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