Ishikawa Nobukatsu
Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Tokyo.
Kekkaku. 2005 Feb;80(2):89-94.
Tuberculosis is a global burden disease, most possibly ranking high among diseases over the coming several decades, with 2 million deaths and over 8 million new cases annually. How can TB be controlled and eradicated quickly in the world? A major answer will be the wider application of the most effective control programme, i.e. DOTS recommended by WHO. But it has been developed in the long try and error efforts, including the ones by Dr. K. Styblo of IUATLD in African countries. The key components of successful TB programme are summarised as follows, which Dr. Kochi of WHO adopted as a global policy package. They are; 1) political commitment, 2) case finding by sputum microscopy, 3) use of short course chemotherapy under supervision, 4) a secured supply of anti-TB drugs, and 5) a standardised recording, reporting and monitoring system. The targets by 2005 are set 85% cure rate and 70% detection rate. By 2002, however, only half the targets have been achieved, and global expansion of DOTS with other strategies need to be strengthened. Emerging threats are HIV epidemic, MDR-TB increase and health sector reform taking place in the world. Stop TB partnership with its office in WHO has been formed to strengthen a global capacity, mobilizing various technical and financial partners. Japan's contribution to the global TB problem started in early 1960s. In the last 40 years, technical cooperation in national TB programme (NTP) has been made through JICA in over 15 countries, including United Arab Emirates. Thailand, Nepal, Afghanistan, Tanzania, Indonesia, Solomon Islands, Yemen, Philippines, Cambodia, Myanmar, Pakistan, Zambia, and China (TB project is on-going in underlined countries). In these projects, capacity strengthening of NTP has been given priority, including construction of national TB center, a model area development, nationwide DOTS expansion in collaboration with WHO or others, supply of anti-TB drugs, TB laboratory network with QA, collaborative operational research. An operational research for community based DOTS and ART is newly started in Zambia under JICA project. Besides, over 1800 doctors and technologists from 90 countries have been trained at Research Institute of Tuberculosis (RIT) through its international training courses in the last 40 years. These courses are organised collaboratively with WHO or other agencies, inviting globally renowned lecturers and ex-participants, and have been reputed widely. We aim not only to teach skills and knowledge but also to motivate them to do something new. This becomes possible only through human relationship in the course. I may need to mention about my personal commitment: First, I have worked to develop a community based TB programme model utilising village health volunteers in Bangladesh in 1980s. This system has now covered over 70% of the total patients in the country through BRAC, local NGO. Secondly, the application of participatory action research (PAR) method in introducing or expanding DOTS in Bangladesh and other countries. Staff members of NTP and local/ peripheral workers participate in the trials and discuss actively in the workshops periodically. This PAR approach empowers both NTP managers and peripheral staff. Through the international cooperation, we aim ultimately at 1) support for self-reliance, 2) empowerment (capacity building for problem finding and solution) of the people concerned, and 3) promotion of global peace without arms.
结核病是一种全球负担疾病,很可能在未来几十年的疾病中排名靠前,每年有200万人死亡,新增病例超过800万。如何在全球迅速控制和消除结核病?一个主要答案将是更广泛地应用最有效的控制方案,即世界卫生组织推荐的直接督导下的短程化疗(DOTS)。但它是经过长期的反复试验努力才得以发展的,包括国际防痨和肺部疾病联盟的K. 斯蒂布洛博士在非洲国家所做的努力。成功的结核病防治方案的关键要素总结如下,世界卫生组织的科奇博士将其作为全球政策包采用。它们是:1)政治承诺;2)通过痰涂片显微镜检查发现病例;3)在督导下使用短程化疗;4)确保抗结核药物的供应;5)标准化的记录、报告和监测系统。到2005年的目标是治愈率达到85%,发现率达到70%。然而,到2002年,仅实现了一半的目标,需要加强DOTS与其他策略在全球的推广。新出现的威胁包括全球艾滋病流行、耐多药结核病增加以及世界范围内的卫生部门改革。已成立了“终止结核病伙伴关系”及其在世卫组织的办事处,以加强全球能力,动员各种技术和财政伙伴。日本对全球结核病问题的贡献始于20世纪60年代初。在过去40年里,通过日本国际协力机构在包括阿拉伯联合酋长国在内的15个以上国家开展了国家结核病防治方案(NTP)方面的技术合作。泰国、尼泊尔、阿富汗、坦桑尼亚、印度尼西亚、所罗门群岛、也门、菲律宾、柬埔寨、缅甸、巴基斯坦、赞比亚和中国(加下划线的国家的结核病项目正在进行中)。在这些项目中,优先加强国家结核病防治方案的能力,包括建设国家结核病中心、发展示范地区、与世卫组织或其他机构合作在全国范围内推广DOTS、供应抗结核药物、建立具备质量保证的结核病实验室网络、开展合作性业务研究。在日本国际协力机构的项目下,赞比亚新启动了一项基于社区的DOTS和抗逆转录病毒治疗的业务研究。此外,在过去40年里,结核病研究所通过其国际培训课程为来自90个国家的1800多名医生和技术人员提供了培训。这些课程是与世卫组织或其他机构合作举办的,邀请了全球知名的讲师和往届学员,声誉广泛。我们的目标不仅是传授技能和知识,而且是激励他们去做新的事情。只有通过课程中的人际关系才能实现这一点。我可能需要提及我的个人贡献:第一,我在20世纪80年代致力于在孟加拉国利用乡村卫生志愿者开发一种基于社区的结核病防治方案模式。现在这个系统通过当地非政府组织孟加拉农村发展委员会覆盖了该国70%以上的患者。第二,在孟加拉国和其他国家引入或推广DOTS时应用参与式行动研究(PAR)方法。国家结核病防治方案的工作人员和当地/周边工作人员参与试验,并定期在研讨会上积极讨论。这种PAR方法增强了国家结核病防治方案管理人员和周边工作人员的能力。通过国际合作,我们最终旨在:1)支持自力更生;2)增强相关人员的能力(培养发现和解决问题的能力);3)促进无军备的全球和平。