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创伤后应激障碍中皮质醇研究结果的现状

Current status of cortisol findings in post-traumatic stress disorder.

作者信息

Yehuda Rachel

机构信息

Psychiatry Department, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA.

出版信息

Psychiatr Clin North Am. 2002 Jun;25(2):341-68, vii. doi: 10.1016/s0193-953x(02)00002-3.

DOI:10.1016/s0193-953x(02)00002-3
PMID:12136504
Abstract

This article summarizes findings of hypothalamic-pituitary-adrenal axis alterations in post-traumatic stress disorder (PTSD) and evaluates likely reasons for the lack of agreement among published studies. Sources of variance caused by methodologic and interpretative differences are highlighted, but the disparate findings are explained as illustrating a more complex neuroendocrinology of PTSD than has previously been described.

摘要

本文总结了创伤后应激障碍(PTSD)下丘脑 - 垂体 - 肾上腺轴改变的研究结果,并评估了已发表研究结果不一致的可能原因。文中强调了方法学和解释性差异导致的变异来源,但不同的研究结果被解释为表明PTSD的神经内分泌学比之前所描述的更为复杂。

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