Polkinghorne Kevan R, McDonald Stephen P, Marshall Mark R, Atkins Robert C, Kerr Peter G
Department of Nephrology, Monash Medical Center, Melbourne, Victoria, Australia.
Am J Kidney Dis. 2004 Apr;43(4):696-704. doi: 10.1053/j.ajkd.2003.11.023.
Native arteriovenous fistula (AVF) prevalence varies significantly among different populations and countries. Physician practice patterns may have a strong influence on access type. We assessed differences in vascular access practice patterns across all treating centers in New Zealand.
Adult (age > or = 18 years) patients on hemodialysis therapy in the year ending September 30, 2001, were studied from the Australian and New Zealand Dialysis and Transplant Association Registry. Multinomial logistic regression was used to assess factors associated with arteriovenous graft (AVG) and catheter use.
Of 772 patients available for analysis, 461 patients (60%) underwent dialysis using an AVF; 122 patients (16%), an AVG; and 189 patients (24%), a catheter. On multivariable analysis, female sex (odds ratio, 5.92; P < 0.001), coronary artery disease (odds ratio, 1.89; P < 0.05), body mass index greater than 30 (odds ratio, 2.55; P < 0.05), and age (odds ratio, 1.03 per year increase; P < 0.001) were associated with an increased likelihood of AVG use. Maori and Pacific Island patients were less likely to use an AVG compared with Caucasians (odds ratio, 0.47; P < 0.05). Predictors of greater likelihood of catheter use were female sex (odds ratio, 3.9; P < 0.001), late referral (odds ratio, 1.60; P < 0.05), and age (odds ratio, 1.02 per year increase; P < 0.001). Proportions of access types varied significantly across the 7 treating centers (AVFs, 32% to 86%; AVGs, 2% to 32%; catheters, 9% to 33%; P < 0.001). After adjusting for confounding factors, significant differences persisted among access types in some centers and the national average.
Certain patient characteristics, such as age and female sex, are associated strongly with increased AVG and catheter use. However, the significant variation in risk across centers suggests more attention needs to be given to physician practice patterns to increase AVF use rates.
自体动静脉内瘘(AVF)的患病率在不同人群和国家之间存在显著差异。医生的实践模式可能对血管通路类型有很大影响。我们评估了新西兰所有治疗中心血管通路实践模式的差异。
从澳大利亚和新西兰透析与移植协会登记处研究了截至2001年9月30日的年度接受血液透析治疗的成年(年龄≥18岁)患者。采用多项逻辑回归分析评估与动静脉移植物(AVG)和导管使用相关的因素。
在772例可供分析的患者中,461例(60%)使用AVF进行透析;122例(16%)使用AVG;189例(24%)使用导管。多变量分析显示,女性(比值比,5.92;P<0.001)、冠状动脉疾病(比值比,1.89;P<0.05)、体重指数大于30(比值比,2.55;P<0.05)和年龄(每年增加的比值比,1.03;P<0.001)与使用AVG的可能性增加相关。与白种人相比,毛利人和太平洋岛民患者使用AVG的可能性较小(比值比,0.47;P<0.05)。使用导管可能性较大的预测因素为女性(比值比,3.9;P<0.001)、延迟转诊(比值比,1.60;P<0.05)和年龄(每年增加的比值比,1.02;P<0.001)。7个治疗中心的血管通路类型比例差异显著(AVF为32%至86%;AVG为2%至32%;导管为9%至33%;P<0.001)。在调整混杂因素后,一些中心和全国平均水平的血管通路类型之间仍存在显著差异。
某些患者特征,如年龄和女性,与AVG和导管使用增加密切相关。然而,各中心风险的显著差异表明,需要更多关注医生的实践模式,以提高AVF的使用率。