Zheng T, Holford T R, Mayne S T, Owens P H, Boyle P, Zhang B, Zhang Y W, Zahm S H
Yale School of Public Health, 60 College Street, New Haven, CT 06520, USA.
Eur J Cancer. 2002 Aug;38(12):1647-52. doi: 10.1016/s0959-8049(02)00138-7.
This case-control study was designed to test the hypothesis that the risk of breast cancer varies by type and colour of the hair colouring products used. A total of 608 cases and 609 controls were included in the study. We found no increased risk associated with the overall use of hair dye products or exclusive use of permanent or temporary types of hair dye products. Among those who reported to have exclusively used semi-permanent types of hair colouring products, some of the ORs were elevated. However, none of the ORs related to age at first use, duration of use, total number of applications, and years since first use, was statistically significant. There was also no increased risk of breast cancer associated with exclusive use of dark or light hair colouring products, or use of mixed types or colours of hair dye products. We also found no increased risk of breast cancer associated with hair dye use based on an individual's reason for using a hair colouring product, such as to cover grey or to change natural hair colour. These data suggest that the use of hair colouring products does not have a major impact on the risk of breast cancer.
使用的染发产品类型和颜色不同,患乳腺癌的风险也会有所不同。该研究共纳入了608例病例和609例对照。我们发现,总体使用染发产品或单独使用永久性或临时性染发产品,均未增加风险。在那些报告仅使用半永久性染发产品的人群中,部分比值比有所升高。然而,与首次使用年龄、使用时长、使用总次数以及首次使用后的年数相关的比值比,均无统计学意义。单独使用深色或浅色染发产品,或使用混合型或混合颜色的染发产品,也未增加患乳腺癌的风险。我们还发现,基于个人使用染发产品的原因(如遮盖白发或改变自然发色),使用染发产品并不会增加患乳腺癌的风险。这些数据表明,使用染发产品对患乳腺癌的风险没有重大影响。