血管紧张素II对大鼠空肠体内液体转运、跨壁电位差和血流的影响。
Effects of angiotensin II on fluid transport, transmural potential difference and blood flow by rat jejunum in vivo.
作者信息
Bolton J E, Munday K A, Parsons B J, York B G
出版信息
J Physiol. 1975 Dec;253(2):411-28. doi: 10.1113/jphysiol.1975.sp011197.
Abstract
A method has been described for the measurement of fluid transport by rat jejunum in vivo over two consecutive 30 min periods. 2. Subpressor infusion rates of angiotensin (0-59 ng/kg per minute) stimulate fluid transport, while high (pressor) infusion rates (590 ng/kg per minute) inhibit fluid absorption. 3. Both the inhibitory and stimulatory effects of angiotensin on fluid transport are not accompanied by any change in the transmural p.d., total blood flow to the jejunum or distribution of blood flow within the wall of the jejunum. 4. These results are discussed in relation to the mechanism of action of angiotensin on fluid transport and its role in sodium and water homoeostasis.
摘要
- 已描述了一种用于测量大鼠空肠在体内连续两个30分钟时间段内液体转运的方法。2. 血管紧张素的亚升压输注速率（0 - 59纳克/千克每分钟）刺激液体转运，而高（升压）输注速率（590纳克/千克每分钟）抑制液体吸收。3. 血管紧张素对液体转运的抑制和刺激作用均未伴随跨壁电位差、空肠总血流量或空肠壁内血流分布的任何变化。4. 就血管紧张素对液体转运的作用机制及其在钠和水平衡中的作用对这些结果进行了讨论。
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