Bell Anthony J, Duggin Geoffrey
Emergency Department, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW, Australia.
Emerg Med (Fremantle). 2002 Jun;14(2):188-90. doi: 10.1046/j.1442-2026.2002.00316.x.
We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. A 40-year-old man became quite suddenly and acutely unwell after receiving treatment from an unregistered naturopath. Methyl salicylate (Oil of Wintergreen) is widely available in many over the counter topical analgesic preparations and Chinese medicated oils. Transcutaneous absorption of the methyl salicylate was enhanced in this case due to the abnormal areas of skin and use of an occlusive dressing. The presence of tinnitus, vomiting, tachypnoea and typical acid/base disturbance allowed a diagnosis of salicylate toxicity to be made. Our patient had decontaminated his skin prior to presentation, limiting the extent of toxicity and was successfully treated with rehydration and establishment of good urine flow.
我们报告了一例因使用含有水杨酸甲酯的草药护肤霜治疗银屑病而引发水杨酸中毒的有趣病例。一名40岁男性在接受一名未注册的自然疗法医生治疗后，突然病情急剧加重。水杨酸甲酯（冬青油）在许多非处方外用止痛制剂和中药油中广泛存在。由于皮肤异常区域以及使用了封闭敷料，该病例中水杨酸甲酯的经皮吸收增强。耳鸣、呕吐、呼吸急促和典型的酸碱紊乱症状使得诊断出水杨酸盐中毒。我们的患者在就诊前已对皮肤进行了去污处理，从而限制了中毒程度，并通过补液和促进良好的尿液排出而成功治愈。
