Inaba Daisuke, Kawasaki Koji, Iijima Youichi, Taguchi Nobuhiro, Hayashida Hideaki, Yoshikawa Tadashi, Furugen Reiko, Fukumoto Emiko, Nishiyama Takashi, Tanaka Keiko, Takagi Okiuji
Department of Preventive Dentistry, Iwate Medical University School of Dentistry, Morioka, Japan.
Community Dent Oral Epidemiol. 2002 Aug;30(4):248-53. doi: 10.1034/j.1600-0528.2002.00042.x.
The influence on enamel fluoride uptake of reducing the NaF concentration of a mouthrinse solution by half, from 0.05-0.025%, was examined in elementary school children.
The participatory elementary school had employed school-based fluoride mouthrinse with 0.05% NaF solution since 1983, and in 1993, the NaF content was lowered to 0.025%. Dental examination and enamel biopsy of maxillary central incisors were performed just before the NaF content reduction for children who had received the daily 0.05% NaF mouthrinse for 2-5 years since 6 years of age. During 1993-95, dental examination and enamel biopsy were undertaken for newly enrolled 6-year-old children, and the same subjects were re-examined after 2 years. The same series of examinations were conducted for the control group, which consisted of children belonging to another elementary school without a fluoride program.
The enamel fluoride concentration of 8-year-old children who used the 0.025% NaF mouthrinse for 2 years was 1810 +/- 535 ppm, reaching the same order as that in children who continued using the 0.05% NaF mouthrinse (1863 +/- 1358 ppm), and was significantly higher than that of children without fluoride programs (1113 +/- 303 ppm). There was no considerable increase of mean DMFT values due to the NaF content reduction.
It was concluded that a daily 0.025% NaF mouthrinse provides the similar fluoride content for enamel as 0.05% NaF mouthrinse as long as the rinsing frequency is maintained.
在小学生中研究将含漱液中氟化钠浓度从0.05%减半至0.025%对牙釉质氟摄取量的影响。
参与研究的小学自1983年起使用含0.05%氟化钠溶液的校内氟化物含漱液,1993年将氟化钠含量降至0.025%。对自6岁起每日使用0.05%氟化钠含漱液2至5年的儿童,在氟化钠含量降低前进行上颌中切牙的牙科检查和牙釉质活检。在1993年至1995年期间,对新入学的6岁儿童进行牙科检查和牙釉质活检,并在2年后对同一批受试者进行复查。对由另一所未开展氟化物项目的小学的儿童组成的对照组进行了相同系列的检查。
使用0.025%氟化钠含漱液2年的8岁儿童的牙釉质氟浓度为1810±535 ppm,与继续使用0.05%氟化钠含漱液的儿童(1863±1358 ppm)处于同一水平,且显著高于未开展氟化物项目的儿童(1113±303 ppm)。由于氟化钠含量降低,平均龋失补指数(DMFT)值没有显著增加。
得出的结论是,只要保持漱口频率,每日使用0.025%的氟化钠含漱液与0.05%的氟化钠含漱液为牙釉质提供的氟含量相似。