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一名曾接受过霍奇金淋巴瘤治疗的患者发生由烟曲霉引起的胸骨骨髓炎。

Sternal osteomyelitis caused by Aspergillus fumigatus in a patient with previously treated Hodgkin's disease.

作者信息

Allen D, Ng S, Beaton K, Taussig D

机构信息

Department of Haematological Oncology and Department of Microbiology, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK.

出版信息

J Clin Pathol. 2002 Aug;55(8):616-8. doi: 10.1136/jcp.55.8.616.

Abstract

This report details the case of a 67 year old woman with sternal osteomyelitis caused by Aspergillus fumigatus. She was diagnosed with Hodgkin's disease in 1975 and was successfully treated with chemotherapy. A lobectomy for recurrence localised to the left lung was complicated nine years later by severe bronchiectasis, for which she required a total left sided pneumonectomy. At surgery, a non-invasive aspergillus was found. She presented eight years later with symptoms that were initially attributed to recurrence of Hodgkins's disease, but on investigation were found to be caused by fungal sternal osteomyelitis. Treatment with itraconazole suspension at a dose of 400 mg daily was successful.

摘要

本报告详细介绍了一名67岁女性因烟曲霉引起胸骨骨髓炎的病例。她于1975年被诊断为霍奇金病,并通过化疗成功治愈。9年后,因左肺复发进行的肺叶切除术并发严重支气管扩张,为此她需要进行左侧全肺切除术。手术时发现了非侵袭性曲霉菌。8年后,她出现症状,最初被归因于霍奇金病复发,但经检查发现是由真菌性胸骨骨髓炎引起的。每日服用400毫克伊曲康唑混悬液治疗成功。

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