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儿童急性化脓性甲状腺炎

Acute suppurative thyroiditis in children.

作者信息

Chi Hsin, Lee Yann-Jinn, Chiu Nan-Chang, Huang Fu-Yuan, Huang Chi-Yu, Lee Kuo-Sheng, Shih Shin-Lin, Shih Bing-Fu

机构信息

Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.

出版信息

Pediatr Infect Dis J. 2002 May;21(5):384-7. doi: 10.1097/00006454-200205000-00007.

Abstract

BACKGROUND

Acute suppurative thyroiditis in children is rare and is often related to a pyriform sinus fistula or thyroglossal duct remnant, especially when it is recurrent.

METHODS

From January, 1985, through December, 2000, 15 children with acute suppurative thyroiditis were treated. Their clinical, laboratory and radiologic findings were reviewed and analyzed.

RESULTS

There were 8 girls and 7 boys, with a mean age at diagnosis of 6.1+/-2.9 years (range, 1.5 to 9.8). A thyroid mass was present on the left in 13 and on the right in 2 (P < 0.05). Fever, neck pain and swelling were the most common symptoms and signs. Seven patients (46.7%) had recurrent disease. Needle aspiration for Gram stain and bacterial cultures were done, and pathogenic organisms were identified on culture in 8 patients but were found only on Gram stain in 2 patients. In one-half of the patients with positive cultures, mixed pathogens were found. The most common organisms isolated were streptococcal species (50%). Barium esophagography was performed in all patients, and 5 (33.3%) had a pyriform sinus fistula on the left. Only 1 of the recurrent patients had a fistula. Thyroid scans were performed in 13 patients, of whom 12 (92.3%) had decreased radioactive uptake. Thyroid function tests were normal in all 15.

CONCLUSIONS

Acute suppurative thyroiditis is usually caused by oropharyngeal flora, resulting in mixed pathogens on culture. Broad spectrum antibiotics should be given once cultures have been obtained. Imaging studies might be helpful in the diagnosis of acute suppurative thyroiditis.

摘要

背景

儿童急性化脓性甲状腺炎较为罕见,常与梨状窝瘘或甲状舌管残余有关,尤其是复发性病例。

方法

回顾性分析1985年1月至2000年12月收治的15例儿童急性化脓性甲状腺炎患者的临床、实验室及影像学资料。

结果

15例患者中,女童8例,男童7例,诊断时平均年龄6.1±2.9岁(范围1.5至9.8岁)。13例患者左侧出现甲状腺肿块,2例右侧出现甲状腺肿块(P<0.05)。发热、颈部疼痛和肿胀是最常见的症状和体征。7例患者(46.7%)病情复发。进行了针吸涂片革兰染色及细菌培养,8例患者培养出致病菌,2例仅在革兰染色时发现细菌。培养结果阳性的患者中,一半分离出混合病原菌。最常见的分离菌是链球菌属(50%)。所有患者均行食管钡餐造影,5例(33.3%)患者左侧有梨状窝瘘。复发病例中仅1例有瘘管。13例患者行甲状腺扫描,其中12例(92.3%)放射性摄取降低。15例患者甲状腺功能检查均正常。

结论

急性化脓性甲状腺炎通常由口咽部菌群引起,培养可发现混合病原菌。获取培养结果后应给予广谱抗生素治疗。影像学检查可能有助于急性化脓性甲状腺炎的诊断。

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