Yamashiro S, Bhatnagar M K, Scott J R, Slinger S J
Res Vet Sci. 1975 Nov;19(3):312-21.
Livers of laying hens of Hy-Line No 934E on low erucic acid rapeseed meals and rapeseed oil were studied. Gross lesions in the livers of hens on experimental diets were moderate to severe fatty degeneration, focal necrosis and moderate to severe haemorrhage. Histological examination revealed oedematous foci and lysis of hepatocytes along with large amounts of lipid droplets in the necrotic lesions. Necrotic lesions were not always associated with large haemorrhages. Connective tissue infiltration of older degenerative and haemorrhagic lesions was not extensive. Abdominal haemorrhage from livers occurred when extensive necrosis in the form of hepatocyte lysis and some vascular changes were present, suggesting hepatocytic degeneration caused by toxic products or their metabolites present in rapeseed by-products.
对海兰934E蛋鸡饲喂低芥酸菜籽粕和菜籽油后的肝脏进行了研究。实验日粮组蛋鸡肝脏的大体病变为中度至重度脂肪变性、局灶性坏死以及中度至重度出血。组织学检查显示，坏死灶有水肿，肝细胞溶解，坏死灶内有大量脂滴。坏死灶并不总是伴有大量出血。较陈旧的变性和出血性病变的结缔组织浸润并不广泛。当出现以肝细胞溶解形式的广泛坏死和一些血管变化时，肝脏会发生腹腔出血，这表明菜籽副产品中存在的有毒产物或其代谢物导致了肝细胞变性。
