Ibrahim I K, Hodges R D, Hill R
Res Vet Sci. 1980 Jul;29(1):68-76.
Liver haemorrhage was studied in laying fowl given diets containing rapeseed meals prepared from seed of varieties of Brassica napus grown in the United Kingdom and from seed of the varieties Tower and Erglu. There was lower mortality from liver haemorrhage in birds given Tower than in those given B napus (UK) meal but haemorrhagic lesions in the liver occurred in all groups of birds given rapeseed meal diets, whichever meal was included. Histological and electron microscopical examination revealed several abnormalities in the structure of the hepatocytes. Early degenerative changes were, enlargement of the intercellular spaces, swelling of the mitochondria, distortion of the rough endoplasmic reticulum profiles, disruption of the hepatic sinusoids, and in the most severely affected areas there were necrotic hepatocytes. These abnormalities were observed in sections from the livers of two hybrid strains of birds given the B napus (UK) or Tower rapeseed meal for four weeks or longer.
对产蛋家禽的肝脏出血情况进行了研究，这些家禽被喂食含有由在英国种植的甘蓝型油菜品种的种子以及Tower和Erglu品种的种子制备的菜籽粕的日粮。喂食Tower菜籽粕的家禽肝脏出血导致的死亡率低于喂食英国甘蓝型油菜籽粕的家禽，但无论包含哪种菜籽粕日粮，所有喂食菜籽粕日粮的家禽组肝脏均出现出血性病变。组织学和电子显微镜检查显示肝细胞结构存在一些异常。早期退行性变化包括细胞间隙增大、线粒体肿胀、粗面内质网轮廓变形、肝血窦破坏，在受影响最严重的区域出现坏死肝细胞。在两个杂交品系的家禽肝脏切片中观察到了这些异常，这些家禽喂食英国甘蓝型油菜籽粕或Tower菜籽粕达四周或更长时间。
