Yamashiro S, Bast T
Res Vet Sci. 1978 Jul;25(1):21-4.
The ultrastructure of the livers of four-week-old White Rock broiler chickens fed diets containing 50% rapeseed meal was examined. Multifocal hepatocytic necrosis was observed in most of the birds fed the experimental diets. Early degenerative changes were swelling of mitochondria and vacuolations of various sizes in the cytoplasm of the hepatocytes. The reticulum fibres seen as bundles of cross striated fibrils were disorganised at the sites of the focal necrosis. Alteration of interfibrillar matrix were considered to be reason for the negative silver stain in the necrotic foci at light microscopic level reported previously. Disruption of the liver framework at the necrotic foci appeared to have caused a rupture of the sinusoids in the birds showing the haemorrhagic syndrome.
对饲喂含50%菜籽粕日粮的4周龄白洛克肉鸡的肝脏超微结构进行了检查。在大多数饲喂实验日粮的鸡中观察到多灶性肝细胞坏死。早期退行性变化为线粒体肿胀和肝细胞胞质内出现大小不一的空泡。可见为横纹状纤维束的网状纤维在局灶性坏死部位紊乱。纤维间基质的改变被认为是先前在光镜水平报道的坏死灶中银染阴性的原因。在出现出血综合征的鸡中，坏死灶处的肝组织框架破坏似乎导致了血窦破裂。
