从短瓣肖槿中分离抗菌脂肪酸。
Isolation of antibacterial fatty acids from Schotia brachypetala.
作者信息
McGaw L J, Jäger A K, van Staden J
机构信息
Research Centre for Plant Growth and Development, School of Botany and Zoology, University of Natal Pietermaritzburg, Private Bag X01, 3209, Scottsville, South Africa.
出版信息
Fitoterapia. 2002 Aug;73(5):431-3. doi: 10.1016/s0367-326x(02)00120-x.
In southern Africa, the roots of Schotia brachypetala are used by traditional healers to treat dysentery and diarrhoea. Activity-directed fractionation of the ethanol extract of the dried leaves yielded 9,12,15-octadecatrienoic (linolenic) acid and methyl-5,11,14,17-eicosatetraenoate. These fatty acids displayed antibacterial activity against the Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus and to a lesser extent, against the Gram-negative Escherichia coli and Klebsiella pneumoniae.
在非洲南部，传统治疗师使用短瓣肖槿的根来治疗痢疾和腹泻。对干燥叶片的乙醇提取物进行活性导向分级分离，得到了9,12,15-十八碳三烯酸（亚麻酸）和5,11,14,17-二十碳四烯酸甲酯。这些脂肪酸对革兰氏阳性菌枯草芽孢杆菌和金黄色葡萄球菌具有抗菌活性，对革兰氏阴性菌大肠杆菌和肺炎克雷伯菌的抗菌活性相对较弱。
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