Iwao Yasuhide, Kawashima Yasuo, Seo Norimasa, Kobayashi Tsutomu, Goto Yasuyuki, Morita Kiyoshi, Irita Kazuo, Tsuzaki Koichi, Dohi Shuji, Tanaka Yoshifumi, Shiraishi Yoshito, Tozaki Youko, Nakao Yasuo
Department of Anesthesiology, Kyorin University School of Medicine, Mitaka 181-8611.
Masui. 2002 Jul;51(7):791-800.
Perioperative mortality and morbidity in Japan for the year 2000 were analyzed with special reference to operative regions. The total number of analyzed cases was 903,086. The percentages for each operative region were as follows, CRANIOTOMY 4.5%, THORACOTOMY 3.5%, HEART and GREAT-VESSELS 3.7%, THORACOTOMY with LAPAROTOMY 0.7%, LAPAROTOMY 30.4%, CESARIAN SECTION 3.3%, HEAD-NECK-ENT 14.7%, CHEST-ABDOMEN-PERINEUM 14.0%, SUPINE 3.6%, EXTREMITY including PERIPHERAL-VESSEL 17.2%, OTHERS 4.4%. The incidence of serious events, including cardiac arrest and severe hypotension and hypoxemia developing to cardiac arrest, was 26.74 per 10,000 anesthetics in all operative regions. The events were observed more frequently in HEART and GREAT-VESSELS 170.39, THORACOTOMY with LAPAROTOMY 85.84 and THORACOTOMY 63.63, and less frequently in CHEST-ABDOMEN-PERINEUM 10.49, CESARIAN SECTION 10.95 and EXTREMITY including PERIPHERAL-VESSEL 13.42. Regarding the prognosis of events, the cases with no sequelae were 63.4% in all operative regions. While there were fewer cases with no sequelae in CRANIOTOMY 49.0%, THORACOTOMY with LAPAROTOMY 43.4% and HEART and GREAT-VESSELS 44.4%, there were more cases in HEAD-NECK-ENT 86.9% and CHEST-ABDOMEN-PERINEUM 89.5%. The incidence of serious events totally attributable to anesthetic management was 5.24 per 10,000 anesthetics in all operative regions. The events were observed more frequently in THORACOTOMY 12.91 and SPINE 8.02, and less frequently in LAPAROTOMY except CESARIAN SECTION 4.11 and EXTREMITY including PERIPHERAL-VESSEL 4.65. The main cause of events in THORACOTOMY was inadequate airway management and in SPINE was inadequate airway management and the overdose or miss selection for drugs. Regarding the prognosis of events totally attributable to anesthetic management, the cases with no sequelae were 91.8% in all operative regions. There were fewer cases with no sequelae in HEART and GREAT-VESSELS 82.6%. The incidence of serious events totally attributable to anesthetic management was one fifth of all serious events in all operative regions. While the total deaths from 903,086 cases, including deaths in the operating room or within 7 postoperative days, were 641 cases (7.10 per 10,000 cases), the deaths totally attributable to anesthesia were 9 cases (0.10 per 10,000 cases).
对2000年日本围手术期的死亡率和发病率进行了分析,并特别参考了手术部位。分析的病例总数为903,086例。各手术部位的百分比情况如下:开颅手术4.5%,开胸手术3.5%,心脏和大血管手术3.7%,胸腹联合手术0.7%,剖腹手术30.4%,剖宫产3.3%,头颈耳鼻喉手术14.7%,胸腹会阴手术14.0%,仰卧位手术3.6%,包括外周血管手术的四肢手术17.2%,其他手术4.4%。在所有手术部位,包括心脏骤停、严重低血压以及发展为心脏骤停的严重低氧血症等严重事件的发生率为每10,000例麻醉中26.74例。这些事件在心脏和大血管手术中发生率为170.39例、胸腹联合手术为85.84例、开胸手术为63.63例,较为常见;而在胸腹会阴手术中为10.49例、剖宫产中为10.95例、包括外周血管手术的四肢手术中为13.42例,发生率较低。关于这些事件的预后,所有手术部位中无后遗症的病例占63.4%。开颅手术中无后遗症的病例较少,为49.0%;胸腹联合手术为43.4%;心脏和大血管手术为44.4%;而头颈耳鼻喉手术中无后遗症的病例较多,为86.9%;胸腹会阴手术中为89.5%。在所有手术部位,完全归因于麻醉管理的严重事件发生率为每10,000例麻醉中5.24例。这些事件在开胸手术中发生率为12.91例、脊柱手术中为8.02例,较为常见;而在除剖宫产外的剖腹手术中为4.11例、包括外周血管手术的四肢手术中为4.65例,发生率较低。开胸手术中事件的主要原因是气道管理不当,脊柱手术中事件的主要原因是气道管理不当以及药物过量或选择错误。关于完全归因于麻醉管理的事件的预后,所有手术部位中无后遗症的病例占91.8%。心脏和大血管手术中无后遗症的病例较少,为82.6%。完全归因于麻醉管理的严重事件发生率是所有手术部位所有严重事件发生率的五分之一。在903,086例病例中,包括手术室死亡或术后7天内死亡,总死亡人数为641例(每10,000例病例中有7.10例),而完全归因于麻醉的死亡人数为9例(每10,000例病例中有0.10例)。