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儿童哮喘患者呼出气体温度与呼出一氧化氮之间的关系。

Relationship between exhaled air temperature and exhaled nitric oxide in childhood asthma.

作者信息

Piacentini G L, Bodini A, Zerman L, Costella S, Zanolla L, Peroni D G, Boner A L

机构信息

Dept of Pediatrics, University of Verona, Italy.

出版信息

Eur Respir J. 2002 Jul;20(1):108-11. doi: 10.1183/09031936.02.00237702.

DOI:10.1183/09031936.02.00237702
PMID:12166556
Abstract

Airway inflammation is a characteristic of asthma. Exhaled nitric oxide (eNO) has been demonstrated to be related to actual levels of airway inflammation in asthmatic patients. The purpose of this study was to investigate whether the temperature of exhaled air is related to eNO levels. Temperature of exhaled air and eNO were measured in 52 asthmatic children with a cross-sectional design. A significant relationship was demonstrated between eNO and temperature of peak and plateau exhaled air temperature. The relationship between both the peak and the plateau values and eNO was more evident when it was corrected for environmental temperature. These results suggest a relationship between exhaled nitric oxide and the temperature of exhaled air in asthmatic patients not treated with systemic steroids.

摘要

气道炎症是哮喘的一个特征。呼出一氧化氮(eNO)已被证明与哮喘患者气道炎症的实际水平相关。本研究的目的是调查呼出气体的温度是否与eNO水平相关。采用横断面设计,对52名哮喘儿童测量了呼出气体的温度和eNO。结果显示,eNO与呼出气体峰值温度及平台期温度之间存在显著相关性。在校正环境温度后,峰值和平台期值与eNO之间的关系更为明显。这些结果表明,在未接受全身性激素治疗的哮喘患者中,呼出一氧化氮与呼出气体温度之间存在关联。

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