规律运动对维持性血液透析患者焦虑、抑郁及生活质量的影响。

Effects of regular exercise on anxiety, depression, and quality of life in maintenance hemodialysis patients.

作者信息

Suh Mi Rye, Jung Hae Hyuk, Kim Soon Bae, Park Jung Sik, Yang Won Seok

机构信息

Department of Nursing, College of Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea.

出版信息

Ren Fail. 2002 May;24(3):337-45. doi: 10.1081/jdi-120005367.

DOI:10.1081/jdi-120005367

PMID:12166700

Abstract

BACKGROUND

Psychological problems such as depression and anxiety are common in hemodialysis patients. In several studies, exercise programs were effective in relieving depression or anxiety in these patients, although not all agree.

PURPOSE

In this study, we evaluated the effects of an exercise program on exercise capacity, anxiety, depression and quality of life in maintenance hemodialysis patients.

METHODS

Twenty hemodialysis patients were enrolled in the study. Six patients were later excluded; two due to anemia, one due to nausea with vomiting during exercise, one due to a neurologic problem, and the other two due to noncompliance. Thus, fourteen patients, 3 men and 11 women, aged 42 +/- 10 years, completed the study. The exercise program composed of bicycle ergometer, treadmill or upper limb ergometer, 60 min per session, 3 times per week, for 12 weeks. At the beginning and the end of the exercise program, the exercise capacity was determined by measuring the maximal oxygen consumption and exercise duration. In addition, psychological tests for the assessment of depression, anxiety and quality of life were performed.

RESULTS

Maximal oxygen consumption was increased from 26.3 +/- 4.6 mL/kg/min to 29.8 +/- 4.9 mL/kg/min (p = 0.013). Exercise duration was 483 +/- 138 s at the start. At the end of the exercise program it was increased to 607 +/-119s (p = 0.002). The score of anxiety was significantly improved from 47.9 +/- 5.9 to 42.8 +/- 6.3 after exercise (p = 0.004). Though it did not reach statistical significance there was a trend of improvement in depression (from 44.8 +/- 8.4 to 39.7 +/- 6.4, p = 0.073). The score of quality of life also showed a significant improvement (from 124.5 +/- 16.5 to 133.6 +/- 19.3, p = 0.031).

CONCLUSION

The results of this study indicate that an appropriate application of exercise program would improve the psychological status in long-term maintenance hemodialysis patients.

摘要

背景

抑郁和焦虑等心理问题在血液透析患者中很常见。在多项研究中，运动项目对缓解这些患者的抑郁或焦虑有效，尽管并非所有人都认同。

目的

在本研究中，我们评估了一项运动项目对维持性血液透析患者的运动能力、焦虑、抑郁和生活质量的影响。

方法

20名血液透析患者参与了本研究。后来排除了6名患者；2名因贫血，1名因运动期间恶心伴呕吐，1名因神经系统问题，另外2名因不依从。因此，14名患者（3名男性和11名女性，年龄42±10岁）完成了研究。运动项目包括使用自行车测力计、跑步机或上肢测力计，每次60分钟，每周3次，共12周。在运动项目开始和结束时，通过测量最大耗氧量和运动持续时间来确定运动能力。此外，还进行了评估抑郁、焦虑和生活质量的心理测试。

结果

最大耗氧量从26.3±4.6毫升/千克/分钟增加到29.8±4.9毫升/千克/分钟（p = 0.013）。运动开始时运动持续时间为483±138秒。在运动项目结束时增加到607±119秒（p = 0.002）。运动后焦虑评分从47.9±５.9显著改善至42.8±6.3（p = 0.004）。尽管未达到统计学显著性，但抑郁有改善趋势（从44.8±8.4至39.7±6.4，p = 0.073）。生活质量评分也显著改善（从124.5±16.5至133.6±19.3，p = 0.031）。