Besnier Florent, Laruelle Eric, Genestier Sandrine, Gié Sophie, Vigneau Cécile, Carré François
AUB Santé, 2 rue Le Guilloux, 35000 Rennes, France.
Nephrol Ther. 2012 Jul;8(4):231-7. doi: 10.1016/j.nephro.2011.10.002. Epub 2011 Nov 18.
Chronic kidney failure (CRF) in addition to cardiovascular comorbidities and aging decrease physical activity capacity. An adapted rehabilitation program might be strongly recommended in this population. The aim of the study is to evaluate a 3 months exercise training program with ergocycle at the anaerobic threshold (AT) during dialysis sessions on effort tolerance, quality of life, blood pressure and lipidic disorders.
Six patients meanly aged 72 were evaluated before (t(0)) and after (t(3)) the rehabilitation program by: maximal cardiorespiratory ergotest, a 6-Minute Walk Test (6MWT) and 2 quality of life tests: Medical Outcome Survey Short Form 36-items and the Kidney Disease Quality of Life (SF 36, KDQol).
Physical activity during dialysis is well tolerated. There was no undesirable event during rehabilitation sessions. The dyspnea and muscular weariness threshold linked to the AT increased meanly by 39% (8.83 ± 0.87 vs. 12.25 ± 1.23 mL/min per kg). Distances walked during 6 MWT increased for all patients (351.83 ± 72.17 vs. 412.80 ± 82 meters) Moreover, physical component scale improved (+4.7), mean systolic blood pressure (-7 mmHg) and mean triglycerides concentration (-19%) decreased.
An exercise training program during dialysis sessions with ergocycle and working intensity based on AT seems safe and an effective alternative to improve the effort functional capacity by hemodialysis patients.
慢性肾衰竭（CRF）以及心血管合并症和衰老会降低身体活动能力。对于这一人群，强烈推荐实施适应性康复计划。本研究的目的是评估一项为期3个月的运动训练计划，该计划在透析期间以无氧阈（AT）进行测力计训练，以观察其对耐力、生活质量、血压和脂质紊乱的影响。
6名平均年龄为72岁的患者在康复计划实施前（t(0)）和实施后（t(3)）接受了以下评估：最大心肺运动试验、6分钟步行试验（6MWT）以及两项生活质量测试：医学结局调查简表36项和肾脏病生活质量量表（SF-36，KDQol）。
透析期间的身体活动耐受性良好。康复训练期间未发生不良事件。与无氧阈相关的呼吸困难和肌肉疲劳阈值平均提高了39%（从8.83±0.87增至12.25±1.23毫升/分钟/千克）。所有患者在6分钟步行试验中的步行距离均有所增加（从351.83±72.17米增至412.80±82米）。此外，身体状况评分提高了（+4.7），平均收缩压降低（-7毫米汞柱），平均甘油三酯浓度降低（-19%）。
在透析期间进行基于无氧阈的测力计运动训练计划似乎是安全有效的，可改善血液透析患者的耐力功能。
