Holstege Christopher P, Baylor Michael R, Rusyniak Daniel E
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia, Charlottesville, Virginia, USA.
Semin Neurol. 2002 Mar;22(1):89-93. doi: 10.1055/s-2002-33051.
Among the most popular and intriguing intoxicants of the Victorian Age, absinthe had all but disappeared after it was banned in nearly all developed countries in the early 1900s. A number of great artists and writers from the late 1800s used absinthe as a social drink, including Vincent van Gogh and Toulouse-Lautrec. A recent resurgence of absinthe use has occurred in Europe and is rapidly spreading to the United States. Despite its increasing popularity limited information exists on the mechanism of action and neurotoxicity of absinthe. This paper reviews some of the historical aspects of absinthe and aims to shed light on the mechanism of action and neurotoxicology of this the Green Fairy.
在维多利亚时代最受欢迎且引人入胜的致醉物中,苦艾酒在20世纪初几乎在所有发达国家被禁后,几乎已销声匿迹。19世纪末的许多伟大艺术家和作家都将苦艾酒用作社交饮品,包括文森特·梵高和图卢兹-劳特累克。近期,苦艾酒在欧洲再度兴起,并迅速蔓延至美国。尽管其愈发流行,但关于苦艾酒的作用机制和神经毒性的信息却很有限。本文回顾了苦艾酒的一些历史方面,旨在阐明这位“绿色精灵”的作用机制和神经毒理学。