Munck af Rosenschöld P M, Ceberg C P, Giusti V, Andreo P
Department of Radiation Physics, Lund University Hospital, Sweden.
Phys Med Biol. 2002 Jul 21;47(14):2397-409. doi: 10.1088/0031-9155/47/14/303.
Photon quality correction factors (kQy) for ionization chamber photon dosimetry in an epithermal neutron beam were determined according to a modified absorbed dose to water formalism which was extended to mixed radiation fields. We have studied two commercially available ionization chambers in the epithermal neutron beam optimized for BNCT at the facility at Studsvik, Sweden. One of the chambers is nominally neutron insensitive; a magnesium-walled detector flushed with pure argon gas (denoted by Mg/Ar). The second chamber has approximately the same sensitivity for neutrons and photons; it is considered a 'tissue equivalent' detector, with A-150 walls flushed with methane-based tissue-equivalent gas (denoted by TE/TE). The kQy-factors in epithermal neutron beams have previously been assumed to be equal to unity or estimated from measurements in clinical accelerator produced photon beams. In this work the kQy-factors have been determined from absorbed dose calculations using cavity theory together with Monte Carlo derived electron fluences obtained with the MCNP4c system for water and PMMA phantoms. The calculated quality correction factors differ substantially from unity, being in the order of 10% for the Mg/Ar detector at shallow phantom depths, and between 2 and 4% for other depths and for the TE/TE chamber.
根据一种扩展到混合辐射场的修正水吸收剂量形式,确定了超热中子束中用于电离室光子剂量测定的光子质量校正因子(kQy)。我们在瑞典Studsvik设施中针对硼中子俘获疗法(BNCT)优化的超热中子束中研究了两种商用电离室。其中一个电离室标称对中子不敏感;它是一个镁壁探测器,充有纯氩气(表示为Mg/Ar)。第二个电离室对中子和光子的灵敏度大致相同;它被认为是一个“组织等效”探测器,其A - 150壁充有基于甲烷的组织等效气体(表示为TE/TE)。以前,超热中子束中的kQy因子被假定等于1,或者根据临床加速器产生的光子束测量值估算。在这项工作中,kQy因子是通过使用空腔理论的吸收剂量计算以及用MCNP4c系统针对水和聚甲基丙烯酸甲酯(PMMA)模体获得的蒙特卡罗导出电子注量来确定的。计算得到的质量校正因子与1有很大差异,对于Mg/Ar探测器,在浅模体深度处约为10%,在其他深度以及对于TE/TE电离室则在2%至4%之间。