Baughman Robert P
University of Cincinnati Medical Center, Interstitial Lung Disease and Sarcoidosis Clinic, Cincinnati, Ohio 45267-0565, USA.
Curr Opin Pulm Med. 2002 Sep;8(5):464-9. doi: 10.1097/00063198-200209000-00021.
The treatment of patients with sarcoidosis remains an important part of management. The role of corticosteroids has been questioned by some, while others have reported its value even in asymptomatic patients with interstitial lung disease. Cytotoxic agents have become standard therapy for some forms of chronic disease. Newer agents that modulate the immune response have been studied. A key cytokine in chronic sarcoidosis appears to be tumor necrosis factor. Drugs that inhibit its release or block its effect have been reported as effective for sarcoidosis.
结节病患者的治疗仍然是管理工作的重要组成部分。一些人对皮质类固醇的作用提出了质疑，而另一些人则报告了其在间质性肺病无症状患者中的价值。细胞毒性药物已成为某些形式慢性病的标准疗法。人们对调节免疫反应的新型药物进行了研究。慢性结节病中的一种关键细胞因子似乎是肿瘤坏死因子。据报道，抑制其释放或阻断其作用的药物对结节病有效。
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