Wright Cameron D, Graham Brian B, Grillo Hermes C, Wain John C, Mathisen Douglas J
Division of General Thoracic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
Ann Thorac Surg. 2002 Aug;74(2):308-13; discussion 314. doi: 10.1016/s0003-4975(02)03613-5.
Pediatric tracheal procedures are uncommon. We reviewed our experience to clarify management and results.
Retrospective single-institution review of pediatric tracheal operations, 1978 to 2001.
One hundred sixteen children were evaluated, mean age 10.4 years (10 days to 18 years). Tracheal pathology was postintubation stenosis (n = 72; 62%), congenital stenosis (n = 23; 20%), neoplasm (n = 8; 7%), tracheomalacia (n = 7; 6%), and trauma (n = 6; 5%). Twenty-nine patients had previous tracheal operations. Thirty-six patients received only a minor procedure. Eighty patients had major operations: tracheal resection (n = 46; 58%), laryngotracheal resection (n = 22; 28%), slide tracheoplasty (n = 7; 9%), and carinal resection (n = 5; 6%). The mean length of airway resected was 3.3 cm (1.5 to 6 cm), which represented 30% of the entire trachea. Twenty-eight patients (35%) had complications. These included tracheomalacia (n = 3), recurrent nerve injury (n = 3), laryngeal edema requiring intubation (n = 2), stroke (n = 1), esophageal leak (n = 1), and lobar collapse (n = 1). Nineteen patients had anastomotic failure: severe restenosis (n = 6), mild restenosis (n = 9), dehiscence (n = 2), dehiscence with tracheoesophageal fistula (n = 1), and tracheoinnominate fistula (n = 1). Two children died (2.5%). Complications were more frequent in children less than 7 years of age (p = 0.05) and after previous operations (p = 0.02). Longer fractions of tracheal resection (> 30%) were more likely to result in anastomotic failure (p = 0.0005). Sixty-four (80%) patients achieved a stable airway free of any airway appliance. All patients with neoplasms are alive.
The principles of adult tracheal operations are directly applicable to children and usually lead to a stable, satisfactory airway. Children tolerate anastomotic tension less well than adults; resections more than 30% have a substantial failure rate.
小儿气管手术并不常见。我们回顾了我们的经验以阐明治疗方法及结果。
对1978年至2001年在单一机构进行的小儿气管手术进行回顾性研究。
共评估了116名儿童,平均年龄10.4岁(10天至18岁)。气管病变包括插管后狭窄(n = 72;62%)、先天性狭窄(n = 23;20%)、肿瘤(n = 8;7%)、气管软化(n = 7;6%)和创伤(n = 6;5%)。29例患者曾接受过气管手术。36例患者仅接受了小手术。80例患者接受了大手术:气管切除术(n = 46;58%)、喉气管切除术(n = 22;28%)、滑动气管成形术(n = 7;9%)和隆突切除术(n = 5;6%)。切除的气道平均长度为3.3 cm(1.5至6 cm),占整个气管的30%。28例患者(35%)出现并发症。这些并发症包括气管软化(n = 3)、喉返神经损伤(n = 3)、需要插管的喉水肿(n = 2)、中风(n = 1)、食管瘘(n = 1)和肺叶萎陷(n = 1)。19例患者出现吻合口失败:严重再狭窄(n = 6)、轻度再狭窄(n = 9)、裂开(n = 2)、伴有气管食管瘘的裂开(n = 1)和气管无名动脉瘘(n = 1)。两名儿童死亡(2.5%)。并发症在7岁以下儿童(p = 0.05)和既往有手术史的儿童中(p = 0.02)更为常见。较长的气管切除比例(> 30%)更有可能导致吻合口失败(p = 0.0005)。64例(80%)患者获得了稳定的气道,无需任何气道装置。所有肿瘤患者均存活。
成人气管手术的原则直接适用于儿童,通常可导致稳定、满意的气道。儿童对吻合口张力的耐受性不如成人;切除超过30%的失败率较高。