Bartsch Dirk-Uwe, Zhu Lijun, Sun P C, Fainman Shaya, Freeman William R
University of California San Diego, UCSD Shiley Eye Center, 9500 Gilman Drive, La Jolla, California 92093, USA.
J Biomed Opt. 2002 Jul;7(3):451-6. doi: 10.1117/1.1483083.
To study the retina in normal subjects with a high-resolution imaging system using adaptive optics for wave front aberration correction.
We used a low-cost 37-element micromachined membrane deformable mirror (MMDM) with a continuous membrane as the reflective surface. A Hartmann-Shack wave front sensor with cooled charge coupled device camera was used to measure the wave front aberration. Zernike polynomials were used to describe the wave front shape. We developed a mirror control system to compensate for wave aberrations. We tested this instrument in normal subjects.
We were able to image the retina in monochromatic laser light and document the increase in resolution. While it is hard to estimate the exact size of the smallest structures in the image, we were able to subjectively grade the image quality. The system is able to compensate for higher order aberrations present in the human eye.
The capabilities of correcting ocular aberrations are limited by the number of adjustable elements in the mirror and the deflection range of the surface. The advantage of the MMDM system is its low cost when compared with other adaptive optics solutions such as piezodriven mirrors and spatial light modulators. This technique may allow for improved resolution for clinical fundus photography.
使用用于波前像差校正的自适应光学高分辨率成像系统研究正常受试者的视网膜。
我们使用了一种低成本的37元素微机械薄膜可变形镜(MMDM),其连续薄膜作为反射表面。使用带有冷却电荷耦合器件相机的哈特曼-夏克波前传感器测量波前像差。泽尼克多项式用于描述波前形状。我们开发了一种镜控制系统来补偿波像差。我们在正常受试者中测试了该仪器。
我们能够在单色激光下对视网膜成像并记录分辨率的提高。虽然很难估计图像中最小结构的确切大小,但我们能够主观地对图像质量进行分级。该系统能够补偿人眼中存在的高阶像差。
校正眼像差的能力受到镜中可调节元件数量和表面偏转范围的限制。与其他自适应光学解决方案(如压电驱动镜和空间光调制器)相比,MMDM系统的优点是成本低。该技术可能会提高临床眼底摄影的分辨率。