波前采样在自适应光学视网膜成像中的影响。
Influence of wave-front sampling in adaptive optics retinal imaging.
作者信息
Laslandes Marie, Salas Matthias, Hitzenberger Christoph K, Pircher Michael
机构信息
Medical University of Vienna, Center of Medical Physics and Biomedical Engineering, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
出版信息
Biomed Opt Express. 2017 Jan 24;8(2):1083-1100. doi: 10.1364/BOE.8.001083. eCollection 2017 Feb 1.
A wide range of sampling densities of the wave-front has been used in retinal adaptive optics (AO) instruments, compared to the number of corrector elements. We developed a model in order to characterize the link between number of actuators, number of wave-front sampling points and AO correction performance. Based on available data from aberration measurements in the human eye, 1000 wave-fronts were generated for the simulations. The AO correction performance in the presence of these representative aberrations was simulated for different deformable mirror and Shack Hartmann wave-front sensor combinations. Predictions of the model were experimentally tested through in vivo measurements in 10 eyes including retinal imaging with an AO scanning laser ophthalmoscope. According to our study, a ratio between wavefront sampling points and actuator elements of 2 is sufficient to achieve high resolution in vivo images of photoreceptors.
与校正元件的数量相比，视网膜自适应光学（AO）仪器中使用了各种不同的波前采样密度。我们开发了一个模型，以描述致动器数量、波前采样点数量与AO校正性能之间的联系。基于人眼像差测量的现有数据，为模拟生成了1000个波前。针对不同的可变形镜和夏克-哈特曼波前传感器组合，模拟了在这些代表性像差存在情况下的AO校正性能。通过对10只眼睛进行体内测量，包括使用AO扫描激光检眼镜进行视网膜成像，对该模型的预测进行了实验测试。根据我们的研究，波前采样点与致动器元件的比例为2就足以在体内获得高分辨率的光感受器图像。
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