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植物和动物的天然免疫:一般激发子与病原体相关分子模式识别之间新出现的相似之处

Innate immunity in plants and animals: emerging parallels between the recognition of general elicitors and pathogen-associated molecular patterns.

作者信息

Nürnberger Thorsten, Brunner Frédéric

机构信息

Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Weinberg 3, D-06120 Halle/Saale, Germany.

出版信息

Curr Opin Plant Biol. 2002 Aug;5(4):318-24. doi: 10.1016/s1369-5266(02)00265-0.

Abstract

Recent findings have highlighted remarkable similarities in the innate pathogen defense systems of plants, animals and insects. Pathogen-associated molecular patterns (PAMP) that are similar to those activating innate immune responses in animals have been shown to mediate the activation of plant defense. Moreover, recognition complexes that are structurally related to animal PAMP receptors are now being discovered in plants, suggesting a common evolutionary origin of pathogen defense systems in higher eukaryotes.

摘要

最近的研究结果突显了植物、动物和昆虫先天病原体防御系统中显著的相似性。已证明与激活动物先天免疫反应的那些分子模式相似的病原体相关分子模式(PAMP)可介导植物防御的激活。此外,目前正在植物中发现与动物PAMP受体在结构上相关的识别复合体,这表明高等真核生物中病原体防御系统有共同的进化起源。

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