Fyda Thomas M, Callaghan John J, Olejniczak Jason, Johnston Richard C
Department of Orthopaedics, University of Iowa College of Medicine, Iowa City 52242, USA.
Iowa Orthop J. 2002;22:8-19.
Between November 1970 and September 1984 the senior author performed fifty-three consecutive total hip arthroplasties with cement in forty-one patients with the diagnosis of osteonecrosis of the femoral head. Five hips in three patients with failed renal transplants requiring chronic hemodialysis were excluded. At the time of final review, a minimum of ten years after the procedure, twenty-one patients (twenty-eight hips) were living, fifteen patients (eighteen hips) had died, and two patients (two hips) were lost to follow-up. A minimum ten-year follow-up radiograph was obtained on twenty-two (79%) of the hips in surviving patients. During the follow-up period 17.4% of hips (eight hips) required revision: 13.0% (six hips) for aseptic loosening, 2.2% (one hip) for sepsis, and 2.2% (one hip) for recurrent dislocation. All eight revisions occurred in patients living at time of final review, giving a revision prevalence of 22.9% (17.1% for aseptic loosening, 2.9% for sepsis, and 2.9% for recurrent dislocation) in patients surviving ten years. The prevalence of revision of the femoral component for aseptic loosening was 6.5% (three hips) for all hips and 9.1% (three hips) in patients surviving at least ten years. The prevalence of femoral aseptic loosening, defined as those components revised for aseptic loosening and those that demonstrated definite or probable radiographic loosening, was 13.0% (six hips) for all hips and 28.6% (six hips) for hips with at least ten-year radiographic follow-up. The prevalence of revision of the acetabular component for aseptic loosening was 13.0% (six hips) for all hips and 18.2% (six hips) in patients surviving at least ten years. The prevalence of acetabular aseptic loosening was 15.2% (seven hips) for all hips and 29.2% (seven hips) for hips with at least ten-year radiographic follow-up. In patients with osteonecrosis of the femoral head survivorship was significantly inferior to that in the senior author's overall patient population with regard to revision for aseptic loosening (p=0.019), revision for acetabular loosening (p=0.01), revision for femoral loosening (p=0.008), and aseptic femoral loosening (p=0.004). Survivorship to aseptic acetabular loosening was not significantly different (p=0.32). Young age at the time of surgery significantly increased the risk of subsequent component loosening (p<0.008) and revision due to aseptic loosening (p<0.002). These findings demonstrate the relatively poor durability of cemented total hip arthroplasty in patients with osteonecrosis of the femoral head as compared to patients with other diagnoses and suggest that the younger age in this patient population compromises results.
1970年11月至1984年9月期间,资深作者连续对41例诊断为股骨头坏死的患者进行了53例全髋关节置换术,均使用骨水泥。排除了3例肾移植失败且需要长期血液透析患者的5个髋关节。在最后一次复查时,即手术至少10年后,21例患者(28个髋关节)仍存活,15例患者(18个髋关节)已死亡,2例患者(2个髋关节)失访。对存活患者中22个(79%)髋关节进行了至少10年的随访X线片检查。在随访期间,17.4%的髋关节(8个髋关节)需要翻修:13.0%(6个髋关节)因无菌性松动,2.2%(1个髋关节)因感染,2.2%(1个髋关节)因复发性脱位。所有8次翻修均发生在最后复查时仍存活的患者中,在存活10年的患者中,翻修率为22.9%(无菌性松动为17.1%,感染为2.9%,复发性脱位为2.9%)。所有髋关节中,股骨部件因无菌性松动的翻修率为6.5%(3个髋关节),至少存活10年的患者中为9.1%(3个髋关节)。股骨无菌性松动的发生率,定义为因无菌性松动而翻修的部件以及显示明确或可能的影像学松动的部件,所有髋关节中为13.0%(6个髋关节),有至少10年影像学随访的髋关节中为28.6%(6个髋关节)。所有髋关节中,髋臼部件因无菌性松动的翻修率为13.0%(6个髋关节),至少存活10年的患者中为18.2%(6个髋关节)。髋臼无菌性松动的发生率,所有髋关节中为15.2%(7个髋关节),有至少10年影像学随访的髋关节中为29.2%(7个髋关节)。在股骨头坏死患者中,就无菌性松动翻修(p = 0.019)、髋臼松动翻修(p = 0.01)、股骨松动翻修(p = 0.008)和无菌性股骨松动(p = 0.004)而言,其生存率明显低于资深作者的总体患者群体。无菌性髋臼松动的生存率无显著差异(p = 0.32)。手术时年龄较小显著增加了随后部件松动的风险(p < 0.008)以及因无菌性松动而翻修的风险(p < 0.002)。这些发现表明,与其他诊断的患者相比,股骨头坏死患者行骨水泥型全髋关节置换术的耐久性相对较差,提示该患者群体年龄较小会影响手术效果。