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髋关节无血管性坏死患者行非骨水泥型全髋关节置换术的功能结局:一项前瞻性研究。

Functional Outcomes of Cementless Total Hip Arthroplasty in Avascular Necrosis of the Hip: A Prospective Study.

作者信息

Karimi Sundas, Kumar Suresh, Ahmed Faheem, Khalid Awais, Farooque Umar, Shahzeen Fnu, Memon Muhammad Ayoob, Hussain Tooba, Basham Maleeha Ali, Kumar Naresh, Yasmin Farah, Hassan Syed Adeel

机构信息

General Surgery, Combined Military Hospital, Karachi, PAK.

Orthopaedics, Jinnah Postgraduate Medical Center, Karachi, PAK.

出版信息

Cureus. 2020 Aug 30;12(8):e10136. doi: 10.7759/cureus.10136.

DOI:10.7759/cureus.10136
PMID:33005548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7524016/
Abstract

Introduction Avascular necrosis occurs due to impaired blood supply to the bone. It can be caused by fractures, dislocations, chronic steroid use, chronic alcohol use, coagulopathy, congenital source, and many other factors. It mostly affects the femoral head (hip joint). Its management can be conservative or invasive. Total hip arthroplasty is the treatment of choice for third and fourth stage avascular necrosis that can be cemented or uncemented. The purpose of this study is to access the functional outcomes of cementless total hip arthroplasty in patients with avascular necrosis of the hip. Materials and methods This prospective study was conducted at a major metropolitan hospital in Karachi, Pakistan over a period of six months. A total of 30 patients of age <60 years, either gender, and a confirmed diagnosis of avascular necrosis of hip with no other associated hip pathologies were included in this study. Demographic features, comorbidities, level of activity, range of movement before the development of avascular necrosis, Charnley's class, and laterality were noted. Cementless press-fit extensively porous-coated acetabular cup with or without cancellous screws and cementless press-fit extensively hydroxyapatite coated femoral stem were used through modified Gibson's posterior approach. The patients were checked for early and late complications, the position of acetabular and femoral components by radiography, and overall performance by Harris Hip Score (HHS) and modified HHS over a period of 12 months. All statistical analyses were performed using Statistical Package for Social Sciences (SPSS) version 19.0 (IBM Corp, Armonk, NY). Results The mean age was 43.9±6.7 years with 21 (70%) patients ranging from 40 to 60 years of age. There were 22 (73%) male and 8 (27%) female patients. Nine (30%) patients had diabetes mellitus, eight (27%) had hypertension, two (7%) had other comorbidities, and eleven (37%) had no comorbidities. A total of 11 (37%) patients were highly active, 18 (60%) were moderately active, and 1 (3%) was non-active before developing avascular necrosis. There were 4 (13%) patients in Charnley's class I, 15 (50%) in Charnley's class II, and 11 (37%) in Charnley's class III. Fifteen (50%) patients were operated on the left side, seven (23%) on the right side, and eight (27%) bilaterally. No significant early or late complications were noted. Acetabular component was found to be anteverted in 22 (73%), retroverted in zero (0%), neutral in 8 (27%), <35 inclined in 0 (0%), 35-50 inclined in 23 (77%), and >50 inclined in 7 (23%) patients, while femoral component was found neutral in 28 (93%), valgus in 2 (7%), and varus in zero (0%) patients on radiography at follow-up. On functional assessment, the HHS was 100% in 27 (90%) patients, 96% in 2 (7%) patients, and 83% in 1 (3%) patient with an average of 99.2%, while 29 (97%) patients had excellent and only 1 (3%) patient had a good outcome on modified HHS. Conclusions Cementless total hip arthroplasty, performed in patients <60 years of age and avascular necrosis of the hip with no other associated hip pathologies, has excellent functional outcomes with no pain, limping, physical deformity, difficulty in walking, difficulty in climbing stairs, difficulty using public transport, difficulty in sitting, or difficulty in wearing shoes and socks. They usually attain normal limb length and range of movement.

摘要

引言

缺血性坏死是由于骨骼血液供应受损所致。它可由骨折、脱位、长期使用类固醇、长期酗酒、凝血功能障碍、先天性因素及许多其他因素引起。其主要影响股骨头(髋关节)。其治疗方法可以是保守的或侵入性的。全髋关节置换术是治疗第三和第四阶段缺血性坏死的首选方法,可采用骨水泥固定或非骨水泥固定。本研究的目的是评估非骨水泥型全髋关节置换术治疗髋关节缺血性坏死患者的功能结局。

材料与方法

这项前瞻性研究在巴基斯坦卡拉奇的一家大型都市医院进行,为期6个月。本研究纳入了30例年龄小于60岁、性别不限且确诊为髋关节缺血性坏死且无其他相关髋关节病变的患者。记录了人口统计学特征、合并症、活动水平、缺血性坏死发生前的活动范围、Charnley分级和侧别。通过改良的Gibson后路,使用非骨水泥压配式多孔涂层髋臼杯(有或无松质骨螺钉)和非骨水泥压配式羟基磷灰石涂层股骨干。对患者进行早期和晚期并发症检查、通过X线检查髋臼和股骨组件的位置,并在12个月期间通过Harris髋关节评分(HHS)和改良HHS评估总体表现。所有统计分析均使用社会科学统计软件包(SPSS)19.0版(IBM公司,纽约州阿蒙克)进行。

结果

平均年龄为43.9±6.7岁,其中21例(70%)患者年龄在40至60岁之间。男性患者22例(73%),女性患者8例(27%)。9例(30%)患者患有糖尿病,8例(27%)患有高血压,2例(7%)患有其他合并症,11例(37%)无合并症。在发生缺血性坏死之前,共有11例(37%)患者活动度高,18例(60%)患者活动度中等,1例(3%)患者不活动。Charnley分级中,I级有4例(13%),II级有15例(50%),III级有11例(37%)。15例(50%)患者在左侧进行手术,7例(23%)在右侧进行手术,8例(27%)双侧进行手术。未发现明显的早期或晚期并发症。随访时X线检查发现,髋臼组件前倾的患者有22例(73%),后倾的患者为0例(0%),中立位的患者有8例(27%),倾斜度<35°的患者为0例(0%),倾斜度在35 - 50°之间的患者有23例(77%),倾斜度>50°的患者有7例(23%);而股骨组件中立位的患者有28例(93%),外翻的患者有2例(7%),内翻的患者为0例(0%)。在功能评估中,HHS评分为100%的患者有27例(90%),96%的患者有2例(7%),83%的患者有1例(算3%),平均为99.2%;而改良HHS评分为优的患者有29例(97%),只有1例(3%)患者评分为良。

结论

对于年龄小于60岁且患有髋关节缺血性坏死且无其他相关髋关节病变的患者,非骨水泥型全髋关节置换术具有出色的功能结局,患者无疼痛、跛行、身体畸形、行走困难、爬楼梯困难、使用公共交通工具困难、坐下困难或穿脱鞋袜困难等问题。他们通常能获得正常的肢体长度和活动范围。

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