Wolter D, Mohr W, Kinzl L
Chirurg. 1975 Oct;46(10):459-62.
2,5 gr. of bone wax (Knochenwachs) were implanted in the iliac crest of 10 sheep. The induction of a foreign body reaction and chronic inflammation was proven demonstrable until the 12th week after implantation of the bone wax. In this period only partial resorption of the wax occurred simultaneously with significantly retarded osseous regeneration. From a clinical point of view it therefore seems necessary when using bone wax to pay particular attention to inflammatory reactions, reduced new bone formation and eventual occurrence of pseudo-arthrosis.
将2.5克骨蜡植入10只绵羊的髂嵴。在植入骨蜡后的第12周，证实可诱发异物反应和慢性炎症。在此期间，仅发生骨蜡的部分吸收，同时骨再生明显延迟。因此，从临床角度看，使用骨蜡时似乎有必要特别注意炎症反应、新骨形成减少以及最终可能出现的假关节。
