Wong T Y, Foster P J, Johnson G J, Seah S K L
Department of Ophthalmology, National University of Singapore, Singapore.
Br J Ophthalmol. 2002 Sep;86(9):963-8. doi: 10.1136/bjo.86.9.963.
To relate indices of education, occupation, and socioeconomic status to ocular dimensions and refraction in an adult population.
A population based, cross sectional survey of adult Chinese aged 40-81 years residing in the Tanjong Pagar district in Singapore. Ocular dimensions, including axial length, anterior chamber depth, lens thickness, and vitreous chamber depth, were measured using an A-mode ultrasound device. Corneal radius of curvature and refraction were determined with an autorefractor, with refraction further refined subjectively, and lens nuclear opacity was graded clinically using the modified Lens Opacity Classification System III score. Data on education, occupation, income, and housing type were obtained from a standardised interview.
Biometric data were available on 951 phakic subjects. After controlling for age, sex, occupation, income and housing type, higher education was associated with longer axial lengths (0.60 mm; 95% confidence interval (CI): 0.34, 0.85, for every 10 years of education), longer vitreous chambers (0.53 mm; 95% CI: 0.30, 0.77), and more myopic refractions (-1.50 dioptres, 95% CI: -2.08, -0.92). Adjustment for axial length attenuated the refractive association of education (-0.68 dioptre, 95% CI: -1.14, -0.21). Similarly, near work related occupations (managers, professionals, and office workers) and higher income were independently associated with longer axial lengths, longer vitreous chambers, and more myopic refractions, and adjustment for axial length attenuated the refractive associations.
Adults with greater education, near work related occupations, and higher income are more likely to have longer axial lengths and vitreous chambers, and more myopic refractions. The refractive associations of education, occupation, and income are largely explained by variations in axial length.
探讨教育程度、职业和社会经济地位指标与成年人群眼部尺寸及屈光状态之间的关系。
对居住在新加坡丹戎巴葛区年龄在40 - 81岁的成年华人进行基于人群的横断面调查。使用A超超声设备测量眼部尺寸,包括眼轴长度、前房深度、晶状体厚度和玻璃体腔深度。使用自动验光仪测定角膜曲率半径和屈光状态,屈光状态再经主观进一步精确测量,并使用改良的晶状体混浊分类系统III评分对晶状体核混浊进行临床分级。通过标准化访谈获取教育程度、职业、收入和住房类型的数据。
951例有晶状体眼受试者获得了生物测量数据。在控制年龄、性别、职业、收入和住房类型后,受教育程度较高者眼轴长度更长(每接受10年教育,眼轴长度增加0.60 mm;95%置信区间(CI):0.34,0.85),玻璃体腔更长(0.53 mm;95% CI:0.30,0.77),近视屈光度数更高(-1.50屈光度,95% CI:-2.08,-0.92)。调整眼轴长度后,教育程度与屈光之间的关联减弱(-0.68屈光度,95% CI:-1.14,-0.21)。同样,与近工作相关职业(经理、专业人员和办公室职员)和高收入独立地与更长的眼轴长度、更长的玻璃体腔和更高的近视屈光度数相关,调整眼轴长度后,这些职业和收入与屈光之间的关联减弱。
受教育程度较高、从事与近工作相关职业以及收入较高的成年人更有可能眼轴长度和玻璃体腔更长,近视屈光度数更高。教育程度、职业和收入与屈光之间的关联很大程度上可由眼轴长度的差异来解释。