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中国人年轻人屈光度和眼生物测量学与身高等因素的关系:安阳市大学生眼研究。

Effect of body stature on refraction and ocular biometry in Chinese young adults: The Anyang University Students Eye Study.

机构信息

Beijing Institute of Ophthalmology, Beijing Tongren Eye Centre, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Anyang Eye Hospital, Anyang, China.

出版信息

Clin Exp Optom. 2021 Mar;104(2):201-206. doi: 10.1111/cxo.13137.

DOI:10.1111/cxo.13137
PMID:32869355
Abstract

CLINICAL RELEVANCE

Large-scale data on the association between body stature with biometry parameters and refraction in young adults facilitates an understanding of myopia development. Taller persons have eyes with more negative refractions, longer axial lengths, deeper anterior chambers, flatter corneas, and higher axial length-corneal radius ratio.

BACKGROUND

To determine the relationship between body stature with ocular biometry and refraction in young adults.

METHODS

This was a cross-sectional university-based study of 16- to 26-year-old students in China. Cycloplegic refraction and corneal curvature were measured using an autorefractor. Ocular parameters, including axial length, anterior chamber depth and lens thickness, were measured using a Lenstar LS900. Data on height and weight were acquired from an annual standardised physical examination and body mass index was calculated.

RESULTS

Of 7,971 participants examined in the school clinics, 5,657 (71.0 per cent) were available in the analysis. After adjusting for age, gender, parental myopia, time outdoors, near work and weight, each centimetre of height increase was associated with more negative refraction of -0.023-D, a 0.032-mm increase in axial length, a 0.003-mm increase in anterior chamber depth, a 0.008-mm increase in corneal curvature, and a 0.001 increase in axial length-corneal radius ratio. With regard to weight, a 1-kg heavier person was more likely to have less negative refraction of 0.011-D, a 0.001-mm increase in anterior chamber depth and a 0.002-mm increase in corneal curvature. A similar pattern of significant associations was also found in body mass index.

CONCLUSION

Taller, young adults tended to have longer eyes, deeper anterior chambers, flatter corneas, higher axial length-corneal radius ratio, and more negative refraction, adjusted for potential confounders. In contrast, heavier and higher body mass index persons are more hyperopic. The differences in stature may partially explain the variation in refraction and ocular biometric parameters.

摘要

临床相关性

关于身高与生物测量参数和年轻人屈光度之间关联的大规模数据有助于了解近视的发展。较高的人眼睛的负折射更多,眼轴更长,前房更深,角膜更平,眼轴-角膜半径比更高。

背景

确定中国 16 至 26 岁年轻人的身高与眼球生物测量和屈光度的关系。

方法

这是一项在中国大学进行的横断面研究,研究对象为 16 至 26 岁的学生。使用自动折射仪测量睫状肌麻痹后的屈光度和角膜曲率。使用 Lenstar LS900 测量眼轴长度、前房深度和晶状体厚度等眼部参数。身高和体重数据来自年度标准化体检,计算体重指数。

结果

在学校诊所检查的 7971 名参与者中,有 5657 名(71.0%)可用于分析。在校正年龄、性别、父母近视、户外活动时间、近距工作和体重后,身高每增加 1 厘米,负折射增加-0.023 屈光度,眼轴长度增加 0.032 毫米,前房深度增加 0.003 毫米,角膜曲率增加 0.008 毫米,眼轴-角膜半径比增加 0.001。至于体重,1 公斤重的人更有可能负折射少 0.011 屈光度,前房深度增加 0.001 毫米,角膜曲率增加 0.002 毫米。在体重指数方面也发现了类似的显著关联模式。

结论

较高的年轻人往往眼睛较长,前房较深,角膜较平,眼轴-角膜半径比更高,负折射更大,调整了潜在的混杂因素。相比之下,体重较重和体重指数较高的人更容易远视。身高的差异可能部分解释了屈光度和眼球生物测量参数的变化。

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