McKinlay A, Dalrymple-Alford J C, Horwood L J, Fergusson D M
Department of Psychology, University of Canterbury, and Christchurch Movement Disorders and Brain Research Group, Christchurch, New Zealand.
J Neurol Neurosurg Psychiatry. 2002 Sep;73(3):281-8. doi: 10.1136/jnnp.73.3.281.
The question of whether any adverse cognitive or psychosocial outcomes occur after mild head injury in early childhood has evoked considerable controversy. This study examined mild head injury before age 10 and potential differences in late childhood/early adolescence as a function of severity of mild injury and age at injury.
A fully prospective longitudinal design tracked a large birth cohort of children. Confirmed cases of mild head injury before age 10 were divided on the basis of outpatient medical attention (n=64-84) or inpatient observation (hospital overnight; n=26-28 ) and compared with the non-injured remainder of the cohort (reference group; n=613-807). A range of pre-injury and post-injury child and family characteristics were used to control for any potential confounds. Outcome after injury before and after age 5 was also assessed.
After accounting for several demographic, family, and pre-injury characteristics, the inpatient but not the outpatient group displayed increased hyperactivity/inattention and conduct disorder between ages 10 to 13, as rated by both mothers and teachers. Psychosocial deficits were more prevalent in the inpatient subgroup injured before age 5. No clear effects were evident for various cognitive/academic measures, irrespective of severity of mild injury or age at injury.
Most cases of mild head injury in young children do not produce any adverse effects, but long term problems in psychosocial function are possible in more severe cases, perhaps especially when this event occurs during the preschool years. The view that all mild head injuries in children are benign events requires revision and more objective measures are required to identify cases at risk.
幼儿期轻度头部损伤后是否会出现任何不良认知或心理社会后果的问题引发了相当大的争议。本研究调查了10岁前的轻度头部损伤以及儿童晚期/青少年早期因轻度损伤严重程度和受伤年龄而产生的潜在差异。
采用完全前瞻性纵向设计对一大群出生队列儿童进行跟踪。10岁前确诊的轻度头部损伤病例根据门诊医疗护理情况(n = 64 - 84)或住院观察情况(住院过夜;n = 26 - 28)进行划分,并与队列中未受伤的其余儿童(参照组;n = 613 - 807)进行比较。一系列受伤前和受伤后的儿童及家庭特征被用于控制任何潜在的混杂因素。还评估了5岁前后受伤后的结果。
在考虑了几个人口统计学、家庭和受伤前特征后,住院组而非门诊组在10至13岁之间表现出多动/注意力不集中和品行障碍增加,这是由母亲和教师评定的。心理社会缺陷在5岁前受伤的住院亚组中更为普遍。对于各种认知/学业指标,无论轻度损伤的严重程度或受伤年龄如何,均未发现明显影响。
幼儿期大多数轻度头部损伤病例不会产生任何不良影响,但在更严重的病例中可能会出现心理社会功能的长期问题,尤其是当这种情况发生在学龄前时。认为儿童所有轻度头部损伤都是良性事件的观点需要修正,并且需要更客观的措施来识别有风险的病例。