Grinkeviciūte Dovile Evalda, Kevalas Rimantas, Saferis Viktoras, Matukevicius Algimantas, Ragaisis Vytautas, Tamasauskas Arimantas
Department of Children's Diseases, Kaunas University of Medicine, Kaunas, Lithuania.
Medicina (Kaunas). 2007;43(11):861-9.
To determine the threshold values of Pediatric Index of Mortality 2 (PIM 2) score, Pediatric Trauma Score (PTS), and Glasgow Coma Scale (GCS) score for mortality in children after severe head injury and to evaluate changes in outcomes of children after severe head injury on discharge and after 6 months.
All children with severe head injury admitted to the Pediatric Intensive Care Unit of Kaunas University of Medicine Hospital, Lithuania, from January 2004 to June 2006 were prospectively included in the study. The severity of head injury was categorized according to the GCS score < or =8. As initial assessment tools, the PTS, postresuscitation GCS, and PIM 2 scores were calculated for each patient. Outcome was assessed according to Glasgow Outcome Scale on discharge and after 6 months.
The study population consisted of 59 children with severe head injury. The group consisted of 37 (62.7%) boys and 22 (37.3%) girls; the mean age was 10.6+/-6.02. The mean GCS, PTS, and PIM 2 scores were 5.9+/-1.8, 4.8+/-2.7, and 14.0+/-19.5, respectively. In terms of overall outcome, 46 (78.0%) patients survived and 13 (22.0%) died. All three scales appeared to be significant predictors of death. Threshold values for which potential mortality in children after severe head injury increased were 10.75 for PIM 2, 3 for PTS and 5 for GCS. PIM 2 score provided the best discrimination between survivors and nonsurvivors.
The threshold values for mortality in children after severe head trauma were PIM 2> or =10.75%, PTS< or =3 and GCS< or =5, and these values were significant risk factors of death in severely head injured children. The changes in outcome for survivals on discharge and after 6 months were statistically significant.
确定儿童严重颅脑损伤后死亡的小儿死亡指数2(PIM 2)评分、小儿创伤评分(PTS)和格拉斯哥昏迷量表(GCS)评分的阈值,并评估严重颅脑损伤儿童出院时及6个月后的结局变化。
前瞻性纳入2004年1月至2006年6月在立陶宛考纳斯医科大学医院儿科重症监护病房收治的所有严重颅脑损伤儿童。根据格拉斯哥昏迷量表评分≤8分对颅脑损伤的严重程度进行分类。作为初始评估工具,为每位患者计算PTS、复苏后GCS评分和PIM 2评分。根据格拉斯哥预后量表在出院时及6个月后评估结局。
研究人群包括59例严重颅脑损伤儿童。该组包括37例(62.7%)男孩和22例(37.3%)女孩;平均年龄为10.6±6.02岁。GCS、PTS和PIM 2评分的平均值分别为5.9±1.8、4.8±2.7和14.0±19.5。就总体结局而言,46例(78.0%)患者存活,13例(22.0%)死亡。所有三个量表似乎都是死亡的重要预测指标。严重颅脑损伤儿童潜在死亡率增加的阈值为PIM 2为10.75、PTS为3、GCS为5。PIM 2评分在幸存者和非幸存者之间提供了最佳区分。
严重颅脑创伤儿童死亡的阈值为PIM 2≥10.75%、PTS≤3和GCS≤5,这些值是严重颅脑损伤儿童死亡的重要危险因素。出院时及6个月后存活者结局的变化具有统计学意义。