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中等弹性动脉内的脉动血流、其建模及弹性的影响。

Pulsatile flow inside moderately elastic arteries, its modelling and effects of elasticity.

作者信息

Pedrizzetti Gianni, Domenichini Federico, Tortoriello Angela, Zovatto Luigino

机构信息

Dipartimento Ingegneria Civile, Università di Trieste, P.le Europa 1, Trieste 34127, Italy.

出版信息

Comput Methods Biomech Biomed Engin. 2002 Jun;5(3):219-31. doi: 10.1080/10255840212874.

Abstract

Pulsatile flow inside a moderately elastic circular conduit with a smooth expansion is studied as a model to understand the influence of wall elasticity in artery flow. The solution of the simultaneous fluid-wall evolution is evaluated by a perturbative method, where the zeroth order solution is represented by the flow in a rigid vessel; the first order correction gives the wall motion and induced flow modification without the need to solve the difficult coupled problem. Such an approach essentially assumes a locally infinite celerity, therefore it represent a good approximation for the fluid-wall interaction in sites of limited extent (branches, stenosis, aneurism, etc.), which include typical situations associated with vascular diseases. The problem is solved numerically in the axisymmetric approximation; the influence of wall elasticity on the flow and on the unsteady wall shear stress is studied in correspondence of parameters taken from realistic artery flow. Attention is posed to the role of phase difference between the incoming pressure and flow pulses.

摘要

研究了具有光滑扩张的中等弹性圆形管道内的脉动流,以此作为一个模型来理解动脉血流中管壁弹性的影响。通过微扰法评估流体 - 管壁同时演化的解,其中零阶解由刚性血管中的流动表示;一阶修正给出管壁运动和诱导的流动修正,而无需解决困难的耦合问题。这种方法本质上假设了局部无限的波速,因此它对于有限范围部位(分支、狭窄、动脉瘤等)的流体 - 管壁相互作用是一个很好的近似,这些部位包括与血管疾病相关的典型情况。该问题在轴对称近似下进行数值求解;对应于从实际动脉血流获取的参数,研究了管壁弹性对流动和非定常壁面剪应力的影响。关注了入射压力和流动脉冲之间相位差的作用。

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