Carmichael Tina B, Walsh Edward P, Roth Stephen J
Department of Respiratory Care, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA.
Respir Care. 2002 Sep;47(9):1002-6.
Venoarterial extracorporeal membrane oxygenation (VA ECMO) has become a valuable technique in the critical care of children with congenital heart disease who require mechanical cardiorespiratory support. The use of VA ECMO in cardiac patients has expanded from an extension of intraoperative cardiopulmonary bypass and now includes rescue therapy during cardiopulmonary resuscitation, temporary circulatory support for reversible heart failure, and bridge support preceding heart or heart/lung transplantation. In the majority of clinical applications VA ECMO is used in reaction to impending or ongoing cardiorespiratory failure and not in anticipation of an induced change in clinical status. We describe the anticipatory use of VA ECMO to prepare a patient with complex cyanotic congenital heart disease for a high-risk interventional cardiac catheterization. A 2.5 kg neonate with severe Ebstein's anomaly of the tricuspid valve and recurrent episodes of life-threatening supraventricular tachycardia was electively cannulated for VA ECMO in the cardiac intensive care unit. She underwent successful electrophysiologic mapping and transcatheter radiofrequency ablation of an accessory conduction pathway, resulting in termination of the tachycardia. Following an uncomplicated ECMO course she was decannulated in the cardiac intensive care unit and subsequently discharged home in stable condition. The case illustrates the proactive use of ECMO during a procedure in which severe hemodynamic instability could be predicted. We discuss this concept of ECMO use in the context of accepted indications for ECMO in cardiac patients and encourage an expanded role for its use to prevent cardiorespiratory collapse in planned interventions on compromised patients who are at risk of acute deterioration.
静脉-动脉体外膜肺氧合(VA ECMO)已成为对需要机械心肺支持的先天性心脏病患儿进行重症监护的一项重要技术。VA ECMO在心脏疾病患者中的应用已从术中体外循环的延伸扩展到现在包括心肺复苏期间的抢救治疗、对可逆性心力衰竭的临时循环支持以及心脏或心肺移植前的过渡支持。在大多数临床应用中,VA ECMO是用于应对即将发生或正在发生的心肺衰竭,而不是预期临床状态会发生改变。我们描述了VA ECMO的预防性应用,即为一名患有复杂青紫型先天性心脏病的患者进行高风险介入性心导管检查做准备。一名体重2.5千克、患有严重三尖瓣埃布斯坦畸形且反复出现危及生命的室上性心动过速的新生儿,在心脏重症监护病房被选择性地插管进行VA ECMO。她成功接受了电生理标测和经导管射频消融附加传导通路,从而终止了心动过速。在经历了一个无并发症的ECMO疗程后,她在心脏重症监护病房拔管,随后病情稳定地出院回家。该病例说明了在可预测严重血流动力学不稳定的手术过程中积极使用ECMO的情况。我们在心脏疾病患者ECMO的公认适应证背景下讨论了这种ECMO应用概念,并鼓励扩大其应用范围,以防止在对有急性恶化风险的受损患者进行计划性干预时发生心肺衰竭。