Spencer Charles H, Bernstein Bram H
Section of Rheumatology, La Rabida Children's Hospital, University of Chicago Children's Hospital, Pritzker School of Medicine, Chicago, Illinois 60649, USA.
Curr Opin Rheumatol. 2002 Sep;14(5):536-41. doi: 10.1097/00002281-200209000-00010.
In contrast to adult rheumatoid arthritis, hips are commonly affected joints in severe, destructive, juvenile rheumatoid arthritis (JRA). Hip disease develops in 30 to 50% of children with JRA. Because of the importance of the hip joint in weight bearing the advent of hip disease in a child with JRA warns of future disability [1, 2]. The challenges for the clinician are to prevent significant hip involvement, to halt further damage when hip disease is noted, and in the event that conservative treatment fails, to guide the child and family through hip arthroplasty and rehabilitation. Recent trends suggest that today's more aggressive treatment approach and more effective drugs are resulting in fewer children with JRA developing into severe hip disease requiring hip surgery. Similarly, with improvements in orthopedic surgery, the results of hip arthroplasty have improved.
与成人类风湿性关节炎不同,在严重的、具有破坏性的青少年类风湿性关节炎(JRA)中,髋关节是常见的受累关节。30%至50%的JRA患儿会出现髋关节疾病。由于髋关节在负重方面的重要性,JRA患儿出现髋关节疾病预示着未来可能会残疾[1,2]。临床医生面临的挑战是预防髋关节的严重受累,在发现髋关节疾病时阻止进一步损伤,以及在保守治疗失败的情况下,指导患儿及其家庭进行髋关节置换手术和康复治疗。最近的趋势表明,如今更积极的治疗方法和更有效的药物使得发展为需要髋关节手术的严重髋关节疾病的JRA患儿数量减少。同样,随着整形外科手术的改进,髋关节置换手术的效果也有所改善。