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奥氮平会引发血清素综合征吗?

Can olanzapine be implicated in causing serotonin syndrome?

作者信息

Haslett Christopher David, Kumar Shailesh

机构信息

Department of Psychiatry, Rotorua Hospital, Rotorua, New Zealand.

出版信息

Psychiatry Clin Neurosci. 2002 Oct;56(5):533-5. doi: 10.1046/j.1440-1819.2002.01050.x.

DOI:10.1046/j.1440-1819.2002.01050.x
PMID:12193243
Abstract

The present paper describes a case of serotonin syndrome (SS), which developed in a patient with bipolar affective disorder after the addition of olanzapine to her regimen of lithium and citalopram. This appears to be the first report that implicates olanzapine with SS. Clinicians should be aware of the risk of SS when adding atypical antipsychotics, such as olanzapine, to serotonergic agents.

摘要

本文描述了一例血清素综合征(SS)病例,该病例发生在一名双相情感障碍患者身上,她在锂盐和西酞普兰治疗方案中加用了奥氮平之后出现了血清素综合征。这似乎是首例将奥氮平与血清素综合征相关联的报告。临床医生在将非典型抗精神病药物(如奥氮平)添加到血清素能药物中时,应意识到血清素综合征的风险。

相似文献

1
Can olanzapine be implicated in causing serotonin syndrome?奥氮平会引发血清素综合征吗?
Psychiatry Clin Neurosci. 2002 Oct;56(5):533-5. doi: 10.1046/j.1440-1819.2002.01050.x.
2
Olanzapine and serotonin toxicity.奥氮平和5-羟色胺毒性。
Psychiatry Clin Neurosci. 2003 Apr;57(2):241-2. doi: 10.1046/j.1440-1819.2003.01110.x.
3
[The change from clozapine to olanzapine--same effect?].
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Recovery from new-onset diabetes in a schizophrenic man after withdrawal of olanzapine.一名精神分裂症男性停用奥氮平后新发糖尿病的康复情况。
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[Augmentation of selective serotonin reuptake inhibitors (SSRI) with atypical antipsychotics in the treatment of depression].[非典型抗精神病药物与选择性5-羟色胺再摄取抑制剂(SSRI)联合用于治疗抑郁症]
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[Fast control of manic or mixed episodes. Atypical neuroleptics for bipolar patients].[躁狂或混合发作的快速控制。双相情感障碍患者使用非典型抗精神病药物]
MMW Fortschr Med. 2003 May 26;145 Suppl 2:86-7.
7
[Hyperglycemia and ketoacidosis associated with olanzapine].[与奥氮平相关的高血糖症和酮症酸中毒]
Nervenarzt. 1999 Sep;70(9):836-7. doi: 10.1007/s001150050520.
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[Olanzapine in the treatment of depressive disorders with psychotic symptoms].奥氮平治疗伴有精神病性症状的抑郁症
Nervenarzt. 1999 Jan;70(1):68-71. doi: 10.1007/s001150050402.
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[Long-term therapy with intuition].[直觉的长期治疗]
MMW Fortschr Med. 2003 May 26;145 Suppl 2:87.
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Olanzapine: a review of its use in the treatment of bipolar I disorder.奥氮平:其用于治疗双相I型障碍的综述。
CNS Drugs. 2001;15(11):871-904. doi: 10.2165/00023210-200115110-00005.

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Reported Cases of Serotonin Syndrome in MDMA Users in FAERS Database.FAERS数据库中报告的摇头丸使用者血清素综合征病例
Front Psychiatry. 2022 Jan 24;12:824288. doi: 10.3389/fpsyt.2021.824288. eCollection 2021.
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Knowledge, Attitude, and Practice (KAP) Study on Serotonin Syndrome Among Neuro Physicians.神经科医生血清素综合征的知识、态度和实践(KAP)研究
Ann Indian Acad Neurol. 2020 Sep-Oct;23(5):638-643. doi: 10.4103/aian.AIAN_603_19. Epub 2020 Feb 7.
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An atypical case of serotonin syndrome with normal dose of selective serotonin inhibitors: A case report.
选择性5-羟色胺再摄取抑制剂常规剂量引发的非典型血清素综合征一例:病例报告
Medicine (Baltimore). 2019 May;98(19):e15554. doi: 10.1097/MD.0000000000015554.
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Serotonin Syndrome Following Septal Myectomy in Association With Fentanyl and Methylene Blue: A Case Report.室间隔心肌切除术联合芬太尼和亚甲蓝治疗后发生血清素综合征:病例报告。
Psychosomatics. 2018 Sep-Oct;59(5):512-516. doi: 10.1016/j.psym.2018.02.001. Epub 2018 Feb 13.
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Serotonin syndrome.血清素综合征
Ochsner J. 2013 Winter;13(4):533-40.