Haslett Christopher David, Kumar Shailesh
Department of Psychiatry, Rotorua Hospital, Rotorua, New Zealand.
Psychiatry Clin Neurosci. 2002 Oct;56(5):533-5. doi: 10.1046/j.1440-1819.2002.01050.x.
The present paper describes a case of serotonin syndrome (SS), which developed in a patient with bipolar affective disorder after the addition of olanzapine to her regimen of lithium and citalopram. This appears to be the first report that implicates olanzapine with SS. Clinicians should be aware of the risk of SS when adding atypical antipsychotics, such as olanzapine, to serotonergic agents.
本文描述了一例血清素综合征(SS)病例,该病例发生在一名双相情感障碍患者身上,她在锂盐和西酞普兰治疗方案中加用了奥氮平之后出现了血清素综合征。这似乎是首例将奥氮平与血清素综合征相关联的报告。临床医生在将非典型抗精神病药物(如奥氮平)添加到血清素能药物中时,应意识到血清素综合征的风险。